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Sign up for news alerts. Neurodegenerative Clinical and Scientific Advisory Board. Request to be contacted. Price: $1.55 / $0.00. RVX-208 ( apabetalone ) is a first-in-class small molecule that inhibits BET bromodomains. Phase 3 clinical trial BETonMACE is expected to be launched this fall with a primary endpoint of relative risk reduction of Major Adverse Cardiac Events (MACE) in high-risk cardiovascular and diabetes mellitus patients. August 04, 2015. July 21, 2015. July 28, 2015. July 02, 2015.

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Sign up for news alerts. Neurodegenerative Clinical and Scientific Advisory Board. Request to be contacted. Price: $1.55 / $0.00. RVX-208 ( apabetalone ) is a first-in-class small molecule that inhibits BET bromodomains. Phase 3 clinical trial BETonMACE is expected to be launched this fall with a primary endpoint of relative risk reduction of Major Adverse Cardiac Events (MACE) in high-risk cardiovascular and diabetes mellitus patients. August 04, 2015. July 21, 2015. July 28, 2015. July 02, 2015.
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2 corporate profile
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6 senior management
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8 clinical steering committee
9 programs
10 high risk cardiovascular disease
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Home - Resverlogix Corp. | resverlogix.com Reviews

https://resverlogix.com

Sign up for news alerts. Neurodegenerative Clinical and Scientific Advisory Board. Request to be contacted. Price: $1.55 / $0.00. RVX-208 ( apabetalone ) is a first-in-class small molecule that inhibits BET bromodomains. Phase 3 clinical trial BETonMACE is expected to be launched this fall with a primary endpoint of relative risk reduction of Major Adverse Cardiac Events (MACE) in high-risk cardiovascular and diabetes mellitus patients. August 04, 2015. July 21, 2015. July 28, 2015. July 02, 2015.

INTERNAL PAGES

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1

Alzheimer's Disease - Resverlogix Corp.

http://www.resverlogix.com/programs/rvx-208-clinical-development/apoa-i-hdl-reverse-cholesterol-transport.html

Sign up for news alerts. BETonMACE Clinical Steering Committee. Renal Clinical Advisory Board. Neurodegenerative Clinical and Scientific Advisory Board. Request to be contacted.

2

BET Platform - Resverlogix Corp.

http://www.resverlogix.com/programs/BET_platform.html

Sign up for news alerts. BETonMACE Clinical Steering Committee. Renal Clinical Advisory Board. Neurodegenerative Clinical and Scientific Advisory Board. Request to be contacted. Utilizing our knowledge of BET proteins and epigenetics, we have identified additional new compounds. Our small molecule candidates have the following characteristics:. Function via selective inhibition of BET proteins. Alter the activity of genes that play a key role in disease in relevant cell models.

3

Apabetalone/RVX-208 Clinical Development - Resverlogix Corp.

http://www.resverlogix.com/programs

Sign up for news alerts. BETonMACE Clinical Steering Committee. Renal Clinical Advisory Board. Neurodegenerative Clinical and Scientific Advisory Board. Request to be contacted. COMPLETED PHASE 2B CLINICAL TRIALS. POST HOC ANALYSIS: SUSTAIN and ASSURE. Data from this analysis demonstrated a 55% relative risk reduction (RRR) in the incidence of MACE in CVD patients, and a more pronounced 77% RRR in patients with a history of diabetes mellitus. Taken together, the combined effects of BET inhibition on ...

4

BET Inhibition - Resverlogix Corp.

http://www.resverlogix.com/programs/rvx-208-moa/BET_Inhibition.html

Sign up for news alerts. BETonMACE Clinical Steering Committee. Renal Clinical Advisory Board. Neurodegenerative Clinical and Scientific Advisory Board. Request to be contacted. Apabetalone is an inhibitor of BET proteins that modulates and improves multiple biological pathways that drive risk in vascular disease. For more information, please click here for the article New Direction in the Summer 2015 Issue of the EBR Journal.

5

High-Risk Cardiovascular Disease - Resverlogix Corp.

http://www.resverlogix.com/programs/rvx-208-clinical-development/cardiovascular-disease-and-atherosclerosis.html

Sign up for news alerts. BETonMACE Clinical Steering Committee. Renal Clinical Advisory Board. Neurodegenerative Clinical and Scientific Advisory Board. Request to be contacted. Acute Coronary Syndrome (ACS). Major Adverse Cardiac Events (MACE). Chronic Kidney Disease (CKD).

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Our lead product, a pan selective BET inhibitor, is in clinical development for treatment of solid tumors, including prostate cancer. Effective August 1, 2016, Zenith Epigenetics became a wholly-owned subsidiary of Zenith Capital Corp., a biotechnology investment company and reporting issuer in all Provinces of Canada. In addition to holding all of the shares of Zenith Epigenetics, Zenith Capital holds all of the royalty preferred shares of Resverlogix Corp. 2016 Zenith Epigenetics Ltd. Legal.

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Resverlogix Corp. RVX:TSX

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The Life Sciences Report. The Life Sciences Report. Alliance for Regenerative Medicine. Resverlogix Seeks Orphan Status for Lead Drug Candidate (8/3/16). With its lead drug candidate apabetalone already in Phase 3 targeting major adverse cardiac events, Resverlogix has expanded its scope by initiating a Phase 1 study of the small molecule to further investigate its potential applications. John Vandermosten, Zacks Equity Research (7/29/16). John Vandermosten, Zacks Small-Cap Research (6/29/16). Resverlogi...

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Home - Resverlogix Corp.

Sign up for news alerts. Neurodegenerative Clinical and Scientific Advisory Board. Request to be contacted. Price: $1.55 / $0.00. RVX-208 ( apabetalone ) is a first-in-class small molecule that inhibits BET bromodomains. Phase 3 clinical trial BETonMACE is expected to be launched this fall with a primary endpoint of relative risk reduction of Major Adverse Cardiac Events (MACE) in high-risk cardiovascular and diabetes mellitus patients. August 04, 2015. July 21, 2015. July 28, 2015. July 02, 2015.

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