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Robert Osazuwa Ness

Research in Statistical Machine Learning and Intelligent Systems in Molecular Biology

http://robertness.github.io/

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Robert Osazuwa Ness | robertness.github.io Reviews

https://robertness.github.io

Research in Statistical Machine Learning and Intelligent Systems in Molecular Biology

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The rise of probabilistic programming and causal inference

https://robertness.github.io/graphical%20models/causal%20inference/probabilistic%20programming/2016/09/11/The-rise-of-probabilistic-programming-and-causal-inference.html

The rise of probabilistic programming and causal inference. Sep 11, 2016. People new to data science often ask me about the fast path to becoming a deep learning expert. I encourage them that the strategic career-move is not to focus on what is hot now, but what will hot in the future. My bet on the next big thing is causal inference. The impetus behind this trend is the growing popularity of probabilistic programming. DAGs are a key element of causal modeling and inference. Indeed, causal reasoning ...

2

Simulating a Phosphorylation Network from KEGG Pathways Part 2

https://robertness.github.io/2015/07/31/Simulating-a-Phosphorylation-Network-from-KEGG-Pathways-Part-2.html

Simulating a Phosphorylation Network from KEGG Pathways Part 2. Jul 31, 2015. Flexible network simulation using a power law. In a previous post. I simulated a phosphorylation network using pathway maps from KEGG. Given the input KEGG network, I simulate random networks with the same number of vertices and the same in and out degree distributions. The trouble with that approach is that the number of vertices is fixed. Here, I demonstrate a more flexible approach with the following steps:. Fit - power....

3

Data Science Needs a New Economics of Experiments

https://robertness.github.io/2016/11/25/Data-Science-Needs-a-New-Economics-of-Experiments.html

Data Science Needs a New Economics of Experiments. Nov 25, 2016. The economics of running an experiment has fundamentally changed. People who tell people how to run experiments need to change too. Statistical experimental design was developed in Ronald Fisher’s era, when the cost of acquiring data was quite high. Before any experiment, one had to think long and hard about the following; * What are the questions I want to ask of the data specifically? Which factors do I want to test exactly? However, with...

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About

https://robertness.github.io/about

I am interested in model-based approaches to machine learning problems, i.e., starting by explicitly building assumptions about the problem domain into a model, and iteratively updating the model with new data and expert feedback. My dissertation research focused on applying methods from Bayesian inference, graphical modeling, and causal inference to systems biology. Some of my work on those topics are listed below. Research in Statistical Machine Learning and Intelligent Systems in Molecular Biology.

5

Simulating a Phosphorylation Network from KEGG Pathways Part 1

https://robertness.github.io/2015/07/30/Simulating-a-Phosphorylation-Network-from-KEGG-Pathways-Part-1.html

Simulating a Phosphorylation Network from KEGG Pathways Part 1. Jul 30, 2015. I am working on simulating network structures with the same structure as the phospho-signaling network a network composed of directed edges representing the phosphorylation of one signaling protein by another. To get an idea of how these networks are structured, I wrote the following script to pull a signaling pathway from the pathway database KEGG. And assemble them into an igraph. I start with the MAPK signaling pathway.

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Robert Osazuwa Ness

Nov 25, 2016. Data Science Needs a New Economics of Experiments. Sep 11, 2016. The rise of probabilistic programming and causal inference. Jul 31, 2015. Simulating a Phosphorylation Network from KEGG Pathways Part 2. Jul 30, 2015. Simulating a Phosphorylation Network from KEGG Pathways Part 1. Mar 12, 2015. Visualizing Performance In Bayesian Network Structure Learning. Nov 20, 2014. Visualizing Signal Flow in Cell Signaling Model. Nov 9, 2014. Visualizing Signal Flow in Neural Network Model. Oct 2, 2014.

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