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The Silverman Group - Northwestern University

Another enzyme inhibition project is related to g aminobutyric acid (GABA) aminotransferase. Compounds that inhibit this enzyme exhibit anticonvulsant activity and are important in the treatment of addiction and epilepsy. We are synthesizing compounds that can act as inactivators of this enzyme and are studying their mechanisms of inactivation. One of our inactivators is currently in clinical trials. Last updated 1/17/2011 World Wide Web Disclaimer and University Policy Statements.

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Another enzyme inhibition project is related to g aminobutyric acid (GABA) aminotransferase. Compounds that inhibit this enzyme exhibit anticonvulsant activity and are important in the treatment of addiction and epilepsy. We are synthesizing compounds that can act as inactivators of this enzyme and are studying their mechanisms of inactivation. One of our inactivators is currently in clinical trials. Last updated 1/17/2011 World Wide Web Disclaimer and University Policy Statements.
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The Silverman Group - Northwestern University | silverman.northwestern.edu Reviews

https://silverman.northwestern.edu

Another enzyme inhibition project is related to g aminobutyric acid (GABA) aminotransferase. Compounds that inhibit this enzyme exhibit anticonvulsant activity and are important in the treatment of addiction and epilepsy. We are synthesizing compounds that can act as inactivators of this enzyme and are studying their mechanisms of inactivation. One of our inactivators is currently in clinical trials. Last updated 1/17/2011 World Wide Web Disclaimer and University Policy Statements.

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1

Publications -- The Silverman Group - Northwestern University

http://www.silverman.northwestern.edu/publications.html

Articles published in American Chemical Society journals from 1996 to 12 months ago are now available. Please visit this link. If you wish to download an ACS article. 1 Silverman, R.B. Olofson, R.A. 1313 The Oxidation of Tungsten Carbonyl in Carbon Tetrachloride. 2 Klayman, D.L. Kenny, D. Silverman, R.B. Tomaszewski, J.E. Shine, R.J. 3681-3686. The Action of Hydrogen Sulfide on Aminoalkanethiosulfuric Acids (Bunte Salts) to Give Di-, Tri-, and Tetrasulfides. J Am Chem. Soc. J Am Chem. Soc. 2924-2925....

2

Photos -- The Silverman Group - Northwestern University

http://www.silverman.northwestern.edu/photos.html

Last updated 1/17/2011 World Wide Web Disclaimer and University Policy Statements.

3

Rick Silverman -- The Silverman Group - Northwestern University

http://www.silverman.northwestern.edu/rick-silverman.html

Evanston, IL 60208-3113. Email: Agman@chem.northwestern.edu. May 12, 1946. Married, 3 children. 9/1/15-present Patrick G. Ryan/Aon Professor. 9/1/04-8/31/15 John Evans Professor of Chemistry, Northwestern University. 9/1/01-8/31/04 Charles Deering McCormick Professor of Teaching Excellence, Northwestern University. 1/1/96-12/31/97 Arthur Andersen Professor of Chemistry and of Biochemistry, Molecular Biology, and Cell Biology; Member of the Institute for Neuroscience, Northwestern University. 7/74 - 9/76 ...

4

People -- The Silverman Group - Northwestern University

http://www.silverman.northwestern.edu/people.html

Hometown: Plover, WI. Undergraduate, Northwestern University. BS Biology, Northern Michigan University, 2006. PhD Medicinal Chemistry, Purdue University, 2011. Post-Doctoral Fellow, former NIH Post-Doctoral Fellow). BS Chemistry, University of Science at Ho Chi Minh City, Vietnam, 2008. PhD Organic Chemistry, University of Houston, 2015. BS Microbiology, University of Wisconsin-Madison, 2015. PhD Chemistry, Northern Illinois University, 2016. Undergraduate, Northwestern University. Associate Professor, E...

5

The Silverman Group - Northwestern University

http://www.silverman.northwestern.edu/index.html

Another enzyme inhibition project is related to g aminobutyric acid (GABA) aminotransferase. Compounds that inhibit this enzyme exhibit anticonvulsant activity and are important in the treatment of addiction and epilepsy. We are synthesizing compounds that can act as inactivators of this enzyme and are studying their mechanisms of inactivation. One of our inactivators is currently in clinical trials. Last updated 7/12/2016 World Wide Web Disclaimer and University Policy Statements.

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FACULTY | CMIDD

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MEDICINAL & SYNTHETIC CHEMISTRY. CHEMINFORMATICS & MOLECULAR MODELING. DRUG DISCOVERY & DEVELOPMENT. Center for Molecular Innovation and Drug Discovery. Design. Create. Innovate. A multidisciplinary enterprise on Northwestern’s Evanston and Chicago campuses, CMIDD engages more than 50 faculty from three Northwestern schools: Feinberg School of Medicine, Weinberg College of Arts and Sciences and McCormick School of Engineering and Applied Science. This outstanding network of leading clinicians a...Researc...

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Joint Appointees: Department of Molecular Biosciences - Northwestern University

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Weinberg College of Arts and Sciences. Department of Molecular Biosciences. Interdisciplinary Biological Sciences Program. 160; bmh@northwestern.edu. 160;Long-range interprotein electron transfer. 160;Morton Building - Room 6-681 - 310 E Superior Chicago IL 60611. 160; l-laimins@northwestern.edu. Papillomaviruses, cervical cancer, epithelila cells, diffrentiation. 160; madhav.mani@northwestern.edu. Developmental biology, gene regulation, cell and tissue mechanics. 160; t-ohalloran@northwestern.edu.

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Weinberg College of Arts & Sciences | International Institute for Nanotechnology

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Skip to Main Content. Message from the Director. Northwestern University Center of Cancer Nanotechnology Excellence. NU-CCNE Oligonucleotide Synthesis and Nanoconstructs Core. Center of Excellence for Advanced Bioprogrammable Nanomaterials. Thrust 1 - Materials and Methods Development. Thrust 2 - Functional Substrates. Thrust 3 - Advanced Biosensing. NTU-Northwestern Institute for Nanomedicine (NNIN). NTU-Northwestern Institute for Nanomedicine Executive Committee. 2016 NNIN Workshop Agenda. In a field l...

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silverman.northwestern.edu silverman.northwestern.edu

The Silverman Group - Northwestern University

Another enzyme inhibition project is related to g aminobutyric acid (GABA) aminotransferase. Compounds that inhibit this enzyme exhibit anticonvulsant activity and are important in the treatment of addiction and epilepsy. We are synthesizing compounds that can act as inactivators of this enzyme and are studying their mechanisms of inactivation. One of our inactivators is currently in clinical trials. Last updated 1/17/2011 World Wide Web Disclaimer and University Policy Statements.

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