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SPOEL.BIO.ED.AC.UK

Spoel Lab

Steven Spoel Lab

http://spoel.bio.ed.ac.uk/

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Spoel Lab | spoel.bio.ed.ac.uk Reviews
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Spoel Lab | spoel.bio.ed.ac.uk Reviews

https://spoel.bio.ed.ac.uk

Steven Spoel Lab

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1

Spoel Lab - Past news

http://spoel.bio.ed.ac.uk/NewsMaster.html

Edinburgh International Science Festival. UK Secretary of State Vince Cable announces new training funds. New enzymatic redox activity uncovered in plant cells. Spoel Research Group features in Bayer's. Bayer Early Excellence in Science Award. Rumana Keyani completes PhD degree. Circadian Redox Signalling in Plant Immunity and Abiotic Stress. Plants prioritize foraging for light over immune responses. Spoel Lab featured in Royal Society Black History Month. Featured article in Nature Reviews Immunology.

2

Spoel Lab - Redox research

http://spoel.bio.ed.ac.uk/Redox.html

Immune Signalling by Redox-Based Post-Translational Modifications. Glutathionylation, and disulfide bonding are examples of reversible oxidative cysteine modifications that have profound effects on protein activity, conformation, interaction, and localization. Thus, these post-translational redox modifications are a powerful tool in cellular signaling ( Spoel. Spoel and Loake, 2011. Spoel and Loake, 2011. In our lab we aim to identify signaling proteins that are subject to regulatory redox modifications ...

3

Spoel Lab - Proteasome research

http://spoel.bio.ed.ac.uk/Proteasome.html

We have previously studied this question using NPR1, a potent transcription coactivator of plant immunity. Our findings suggest a model in which NPR1 recruits PolII to target genes before being ubiquitinylated and degraded by the proteasome, thereby returning the target gene promoter to the initial state ( Figure 1. Thus, in this model the rate of coactivator (i.e. NPR1) turnover directly dictates its transcriptional activity and thus, the amount of gene expression (Spoel. Introduction to our research.

4

Spoel Lab - News

http://spoel.bio.ed.ac.uk/News16.html

Insights into plant growth could curb need for fertilisers. New insights into how plants regulate their absorption of an essential nutrient could help avoid pollution caused by excess use of fertiliser. Edinburgh, November 12, 2014. New insights into how plants regulate their absorption of an essential nutrient could help avoid pollution caused by excess use of fertiliser. They found that when nitrogen is absorbed, plant cells produce nitric oxide, which acts as a signalling molecule. The scientists say ...

5

Spoel Lab

http://spoel.bio.ed.ac.uk/index.html

Welcome to the Spoel Lab. Our lab explores the mechanisms by which multicellular organisms reprogram gene expression in response to changes in their environment, a skill that is vital for cells and organisms to survive. The Royal Society's science policy blog releases article on 'Feeding the world'. New Article published in. Current Opinion in Plant Biology. Sophie Kneeshaw completes PhD degree. European Research Council announces Starting Grant for Spoel Research Group. James Furniss completes PhD degree.

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Spoel Lab

Welcome to the Spoel Lab. Our lab explores the mechanisms by which multicellular organisms reprogram gene expression in response to changes in their environment, a skill that is vital for cells and organisms to survive. Royal Society Summer Science Exhibition. Edinburgh International Science Festival. The Spoel Research Group will be participating in this year's Edinburgh International Science Festival. Our own Eleanor Adams. Will be running activies in the Bio-Discoveries lab from 4-8 April 2015.

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