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spRNA | self penetrating RNA for therapy| self penetrating RNA for therapy
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spRNA | self penetrating RNA for therapy | sprna.com Reviews
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Contact | spRNA
http://www.sprna.com/partnering
In order to develop the therapeutic potential of spRNA molecules we are seeking for partners. Please, contact us at. SpRNA self penetrating RNA. SpRNA 2016 Privacy Policy.
self penetrating RNA | spRNA
http://www.sprna.com/self-penetrating-rna
We discovered that RNA molecules alone, without any transfection reagent, can spontaneously penetrate cells. To this end the RNA must have:. A « carrier » sequence (. A poly-G stretch) attached to the sequence of interest. The correct counter ion (. The presence of a dication in the formulating solution (. In those conditions, RNA molecules penetrate in cells where they can exert their activities such as for example immunostimulation through engagement of endosomal Toll Like Receptors.
Immunotherapy against infections | spRNA
http://www.sprna.com/self-penetrating-rna/immunotherapy-against-infections
The immune system can control infectious agents and eventually eliminate them from the body (sterilizing immunity). Eventually, the pathogens controlled by the immune system may not completely disappear and remain latent . SpRNA self penetrating RNA. SpRNA 2016 Privacy Policy.
Immunotherapy against cancer
http://www.sprna.com/sel-penetrating-rna/immunotherapy-against-cancer
Août 16, 2014 at 20:31. Vaccination consists in inducing immunity (T-cells and B-cells) against a precise antigen (or precise antigens) that is (are) expressed in the cancer cells. As any vaccines, anti-cancer vaccines have little side effects. Thus, they hold the promise of safe anti-cancer therapies. Only one anti-cancer vaccine is on the market: Provenge from Dendreon Corporation is used against prostate carcinoma.See www.dendreon.com. View all posts by: spRNA. Laquo; Previous post. Next Post ».
Toll Like Receptors | spRNA
http://www.sprna.com/self-penetrating-rna/toll-like-receptors
Toll Like Receptors are membrane proteins expressed in a wild range of cells, particularly in immune cells. They scan extracellular and intracellular spaces in order to sense infections or pathological situations (for example uncontrolled cell death). Thereby they signal Danger . SpRNA self penetrating RNA. SpRNA 2016 Privacy Policy.
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spRNA | self penetrating RNA for therapy
SpRNA – self penetrating RNA. We discovered that RNA molecules alone, without any transfection reagent, can spontaneously penetrate cells. To this end the RNA must have following things. Our PCT patent entitled. PHARMACEUTICAL COMPOSITION CONSISTING OF RNA HAVING ALKALI METAL AS COUNTER ION AND FORMULATED WITH DICATIONS. In order to develop the therapeutic potential of spRNA molecules we are seeking for partners. Please, contact us at. SpRNA 2015 Privacy Policy.
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