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Diazeniumdiolate Chemistry as a Platform for Designing Nitric Oxide (NO)- and Nitroxyl (HNO)-Based Clinical ApplicationsNitric Oxide Research in our Chemistry Section - Website
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Diazeniumdiolate Chemistry as a Platform for Designing Nitric Oxide (NO)- and Nitroxyl (HNO)-Based Clinical Applications | star.ncifcrf.gov Reviews
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Nitric Oxide Research in our Chemistry Section - Website
Site History and Acknowledgements
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Glycosylated Diazeniumdiolates as Antimicrobial Agents. Sharing Tools and Resources (STAR). Glycosylated Diazeniumdiolates as Antimicrobial Agents. And its metabolism to NO. Last Updated: Monday, March 4, 2013.
Cardiovascular
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Synthesis and Wound Healing Properties of PAN/NO, a polymeric diazeniumdiolate, and PROLI/NO , an Ultrafast NO Donor
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Sharing Tools and Resources (STAR). Synthesis and Wound Healing Properties of PAN/NO, a polymeric diazeniumdiolate, and PROLI/NO , an Ultrafast NO Donor. NO has multiple functions in wound healing. We have developed NO-releasing polymers such as the poly(acrylonitrile)/NO adduct (PAN/NO). This material has proven useful in wound healing applications, e.g., to reduce neointimal hyperplasia after vascular surgery ( DeRosa et al., 2007. The ultrafast NO donor PROLI/NO. Last Updated: Monday, March 4, 2013.
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Diazeniumdiolate Chemistry as a Platform for Designing Nitric Oxide (NO)- and Nitroxyl (HNO)-Based Clinical Applications
Sharing Tools and Resources (STAR). Diazeniumdiolate Chemistry as a Platform for Designing Nitric Oxide (NO)- and Nitroxyl (HNO)-Based Clinical Applications. Nitric oxide is a potent and multifaceted bioregulatory agent. Named Molecule of the Year by Science in 1992, it was the focus of the 1998 Nobel Prize in Physiology or Medicine. Our research is aimed at targeting NO to specific sites in the body for important therapeutic applications using NO-releasing compounds called diazeniumdiolates.
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