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The Luikart Laboratory - Home

The Luikart Laboratory is studying molecular mechanisms of synapse formation and activity dependent plasticity

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The Luikart Laboratory - Home | synapticplasticity.com Reviews

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The Luikart Laboratory is studying molecular mechanisms of synapse formation and activity dependent plasticity

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1

The Luikart Laboratory - Data Gallery

http://www.synapticplasticity.com/data-gallery

Immunohistochemical Staining of Pten Knockout. Co-Injection of 2 Lentiviruses. Co-Injection of Retrovirus and AAV. Retroviral Labeling of Dendritic Spines. 2-Photon Imaging of Spines in Acute Slices. Perforant Pathway onto Newborn Neurons. Bryan W. Luikart, PhD. Geisel School of Medicine. 1 Medical Center Dr. Lebanon, NH 03756.

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The Luikart Laboratory - Publications

http://www.synapticplasticity.com/publications

Bryan W. Luikart, PhD. Geisel School of Medicine. 1 Medical Center Dr. Lebanon, NH 03756.

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The Luikart Laboratory - Home

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Bryan W. Luikart, PhD. Geisel School of Medicine. 1 Medical Center Dr. Lebanon, NH 03756.

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The Luikart Laboratory - The Laboratory

http://www.synapticplasticity.com/the-laboratory

The laboratory is set up to design and package novel viruses,evaluate the efficacy of genetic manipulation. Stereotaxically inject the viruses. And evaluate the impact of the molecular manipulation using imaging and whole cell electrophysiology. In addition to these in-lab capabilities we have access to a number of useful core facilities including the Zeiss LSM510 confocal microscope and a Prairie two-photon microscope with two workstations. Viral Packaging - Cell Culture. Bryan W. Luikart, PhD.

5

The Luikart Laboratory - Personnel

http://www.synapticplasticity.com/personnel

Bryan W. Luikart. Geisel School of Medicine at Dartmouth. Department of Physiology and Neurobiology. Michael R. Williams. Graduate Students and Medical Students. Patrick R. Skelton. Stephanie A. Getz. James R. Howe '17. Stephen K. Ofori Jr. '17. Anissa D. Gladney '18. Christian P. Rizzuto '18. Scott J. Geis '19. Josephina S. Lin '19. Catherine J Fricano Kugler, PhD - Postdocotoral Fellow. Dan Geschwind Laboratory, UCLA. Tyrone DeSpenza Jr. - MD-PhD student, Yale. Derek R. Racine. Emily S. Li.

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The Luikart Laboratory - Home

Neuronal activity impacts how newborn neurons integrate into functional synaptic circuits. This activity dependent sculpting of synaptic circuitry during development and at a slower pace in the adult, represents a type of synaptic plasticity whereby neuronal connectivity slowly changes over time. We focus on performing stable, precise, and well characterized genetic manipulations. Systems to gain molecular insight into the physiologically relevant phenotypes we uncover. Bryan W. Luikart, PhD.

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