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Zhong Lab - Research

We discovered transposon-mediated re-wiring of transcription networks that govern pre-implantation embryonic development [. 2010] We contributed to initiating comparative epigenomics, a research field that studies genomic functions by cross-species epigenomic comparison [. 2012] We contributed to the derivation of the rules of dynamic gene regulation and temporal epigenomic changes [. Single cell analysis of cell fate. Evolution of mammalian gene regulatory networks. We brought evolutionary biology ideas...

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Zhong Lab - Research | systemsbio.ucsd.edu Reviews
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We discovered transposon-mediated re-wiring of transcription networks that govern pre-implantation embryonic development [. 2010] We contributed to initiating comparative epigenomics, a research field that studies genomic functions by cross-species epigenomic comparison [. 2012] We contributed to the derivation of the rules of dynamic gene regulation and temporal epigenomic changes [. Single cell analysis of cell fate. Evolution of mammalian gene regulatory networks. We brought evolutionary biology ideas...
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Zhong Lab - Research | systemsbio.ucsd.edu Reviews

https://systemsbio.ucsd.edu

We discovered transposon-mediated re-wiring of transcription networks that govern pre-implantation embryonic development [. 2010] We contributed to initiating comparative epigenomics, a research field that studies genomic functions by cross-species epigenomic comparison [. 2012] We contributed to the derivation of the rules of dynamic gene regulation and temporal epigenomic changes [. Single cell analysis of cell fate. Evolution of mammalian gene regulatory networks. We brought evolutionary biology ideas...

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systemsbio.ucsd.edu systemsbio.ucsd.edu
1

Zhong Lab - Publications

http://systemsbio.ucsd.edu/publication.html

Mapping RNA-RNA interactome and RNA structure in vivo by MARIO. Tri C Nguyen, Xiaoyi Cao, Pengfei Yu, Shu Xiao, Jia Lu, Fernando H. Biase, Bharat Sridhar, Norman Huang, Kang Zhang, Sheng Zhong. Lens regeneration using endogenous stem cells with gain of visual function. 531: 323-328. Abstract. GeNemo: a search engine for web-based functional genomic data. Yongqing Zhang, Xiaoyi Cao, Sheng Zhong. In press. Text. News coverage: HIT Consultant. Fernando H. Biase, Xiaoyi Cao, Sheng Zhong. Comparative epigenom...

2

Zhong Lab - Publications

http://systemsbio.ucsd.edu/data.html

Mapping RNA RNA interactome and RNA structure in vivo by MARIO. MARIO technology reveals RNA-RNA interactions by sequencing. MARIO sequencing reads were generated from mouse embryonic stem cells and mouse brain. Nguyen et al., Mapping RNA RNA interactome and RNA structure in vivo by MARIO. Nature Communications. Cell fate inclination within 2-cell and 4-cell mouse embryos revealed by single-cell RNA sequencing. Doi: 10.1101/gr.177725.114. Single-cell gene expression data of 96 genes generated by Fluidigm...

3

Zhong Lab - News

http://systemsbio.ucsd.edu/news.html

Sheng received Pioneer Award from NIH. This award recognizes exceptional scientists with groundbreaking research. NIH granted $20 million to the 4D Nucleome. Organizational hub. Sheng serves as the contact PI. In collaboration with Bing Ren and Kang Zhang, we received an R01 grant to study non-coding genomic variations. Kara Johnson received the 2nd year fellowship on NIH cardiovascular training grant. Fernando Biase becomes an assistant professor at Auburn University. Lab featured in Engineering news.

4

Zhong Lab - Research

http://systemsbio.ucsd.edu/index.html

We discovered transposon-mediated re-wiring of transcription networks that govern pre-implantation embryonic development [. 2010] We contributed to initiating comparative epigenomics, a research field that studies genomic functions by cross-species epigenomic comparison [. 2012] We contributed to the derivation of the rules of dynamic gene regulation and temporal epigenomic changes [. Single cell analysis of cell fate. Evolution of mammalian gene regulatory networks. We brought evolutionary biology ideas...

5

Zhong Lab - Courses

http://systemsbio.ucsd.edu/courses.html

BNFO 285 Statistical Learning in Bioinformatics. BENG 183 Applied Genomic Technology. Fall 2013, Fall 2015. BENG 130 Thermodynamics and Kinects for Biotechnology. BENG 207 High-throughput approaches in cell biology. BENG 168 Molecular Bioengineering. Courses taught at Univ Illinois. BIOE598 Gene Regulatory Networks. Girls Adventures in Mathematics, Engineering, and Science (G.amE.S.). Bioinformatics, photo 1. Stem cell and Diabetes), Summer 2010. BIOE398 Statistics and Systems Biology.

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Zhong Lab - Research

We discovered transposon-mediated re-wiring of transcription networks that govern pre-implantation embryonic development [. 2010] We contributed to initiating comparative epigenomics, a research field that studies genomic functions by cross-species epigenomic comparison [. 2012] We contributed to the derivation of the rules of dynamic gene regulation and temporal epigenomic changes [. Single cell analysis of cell fate. Evolution of mammalian gene regulatory networks. We brought evolutionary biology ideas...

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