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Systems Immunity

The Systems Immunity Program. A Systems Biology approach to immunology research. The overall goal of this program is to identify and characterize novel regulators of the immune response to NIAID Priority Pathogens. The knowledge and insights garnered from these efforts will help to guide the development of improved vaccines and therapeutics against infectious diseases that continue to affect us all. Going forward with genetics: recent technological advances and forward genetics in mice. Jun 12, 2014.

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CONTACTS AT SYSTEMSIMMUNITY.ORG

Seattle Biomedical Research Institute

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Seattle Biomedical Research Institute

Seattle Biomedical Research Institute

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Systems Immunity | systemsimmunity.org Reviews
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The Systems Immunity Program. A Systems Biology approach to immunology research. The overall goal of this program is to identify and characterize novel regulators of the immune response to NIAID Priority Pathogens. The knowledge and insights garnered from these efforts will help to guide the development of improved vaccines and therapeutics against infectious diseases that continue to affect us all. Going forward with genetics: recent technological advances and forward genetics in mice. Jun 12, 2014.
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1 systems immunity
2 background
3 resources
4 learn more
5 publications and data
6 highlighted publications
7 recent posts
8 no comments
9 our consortium partners
10 2015 systems immunity
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Systems Immunity | systemsimmunity.org Reviews

https://systemsimmunity.org

The Systems Immunity Program. A Systems Biology approach to immunology research. The overall goal of this program is to identify and characterize novel regulators of the immune response to NIAID Priority Pathogens. The knowledge and insights garnered from these efforts will help to guide the development of improved vaccines and therapeutics against infectious diseases that continue to affect us all. Going forward with genetics: recent technological advances and forward genetics in mice. Jun 12, 2014.

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Systems Immunity » Background

http://www.systemsimmunity.org/background

The Systems Immunity Program. Figure from Review by Beutler and Goodnow. Mamm Genome (2011) 22:1-5 DOI 10.1007/s00335-010-9312-4. The Innate Immune Response. The Adaptive Immune Response. The Scope of Our Investigations. The long-term goal of this program is to provide new approaches for the development of improved vaccines or therapeutics directed against human disease caused by emerging/reemerging pathogens. Theme by Fizzy Inc.

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Systems Immunity » About

http://www.systemsimmunity.org/about

The Systems Immunity Program. Systems Immunity is a gateway to information and resources being developed under NIH/NIAID. Grant , "Systems Approach to Immunity and Inflammation" (. U19AI100627). The overall goal of this program is to identify and characterize novel regulators of the immune response to NIAID Priority Pathogens. Continue to be accessible at www.SystemsImmunology.org. The Scripps Research Institute. Richard Ulevitch, PhD. 8211; Dr. Ulevitch provides overall guidance and oversight of the...

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Systems Immunity » Publications

http://www.systemsimmunity.org/publications

The Systems Immunity Program. Publications and Data Sets. Repository links tied to publications also appear below with their respective citation. Delayed control of herpes simplex virus infection and impaired CD4 T-cell migration to the skin in mouse models of DOCK8 deficiency. Flesch IE, Randall KL, Hollett NA, Di Law H, Miosge LA, Sontani Y, Goodnow CC, Tscharke DC. Immunol Cell Biol. 2015 Mar 17. doi: 10.1038/icb.2015.32. [Epub ahead of print]. Zunder ER, Lujan E, Goltsev Y, Wernig M, Nolan GP. Pallad...

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Systems Immunity » Resources

http://www.systemsimmunity.org/resources

The Systems Immunity Program. A database of phenotypes and mutations produced through random germline mutagenesis with ENU. A missense mutation library at the Australian National University. A web-based platform for flow cytometry software development, data sharing, and result publication. Resources for exploring immune system data. Theme by Fizzy Inc.

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Systems Immunity » The Systems Immunity Program

http://www.systemsimmunity.org/program

The Systems Immunity Program. The Systems Immunity Program. Application of Systems-Guided Forward Genetics to Studies of Immune Regulation. We have developed a strategy that integrates recent technological advances to maximally exploit the power of ENU-mutagenesis and systems-biology to identify novel regulators of immune responses and determine their mechanism of action. Our overall approach is depicted below. To explore the individual projects and the role of each core please click on the figure.

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Systems Immunity

The Systems Immunity Program. A Systems Biology approach to immunology research. The overall goal of this program is to identify and characterize novel regulators of the immune response to NIAID Priority Pathogens. The knowledge and insights garnered from these efforts will help to guide the development of improved vaccines and therapeutics against infectious diseases that continue to affect us all. Going forward with genetics: recent technological advances and forward genetics in mice. Jun 12, 2014.

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