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Musings on "teleogenomics"/"telic memetics". Tuesday, September 22, 2009. Nano-intentionality and Molecular Autonomous Agents. Intrinsic intentionality and inherent goal-directedness of eukaryotic cells is defended by Tecumseh Fitch. And minimal molecular autonomous agents are characterized in " On emergence, agency, and organization. By Stuart Kauffman and Philip Clayton). The "aboutness" and "goal-directedness" of eukaryotic cells and how it relates to nano-intentionality is defined as follows (p14):.

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Musings on teleogenomics/telic memetics. Tuesday, September 22, 2009. Nano-intentionality and Molecular Autonomous Agents. Intrinsic intentionality and inherent goal-directedness of eukaryotic cells is defended by Tecumseh Fitch. And minimal molecular autonomous agents are characterized in On emergence, agency, and organization. By Stuart Kauffman and Philip Clayton). The aboutness and goal-directedness of eukaryotic cells and how it relates to nano-intentionality is defined as follows (p14):.

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Teleomechanist | teleomechanist.blogspot.com Reviews

https://teleomechanist.blogspot.com

Musings on "teleogenomics"/"telic memetics". Tuesday, September 22, 2009. Nano-intentionality and Molecular Autonomous Agents. Intrinsic intentionality and inherent goal-directedness of eukaryotic cells is defended by Tecumseh Fitch. And minimal molecular autonomous agents are characterized in " On emergence, agency, and organization. By Stuart Kauffman and Philip Clayton). The "aboutness" and "goal-directedness" of eukaryotic cells and how it relates to nano-intentionality is defined as follows (p14):.

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teleomechanist.blogspot.com

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Teleomechanist: August 2008

http://teleomechanist.blogspot.com/2008_08_01_archive.html

Musings on "teleogenomics"/"telic memetics". Saturday, August 16, 2008. Putting cytosine deamination to work. The effect of cytosine deamination on a random pool of amino acids and how it might facilitate evolution has been described. Cytosine deamination also does not result in any stop codon formation. Briefly describes a few more optimal features of the genetic code as discussed in more detail by Itzkovitz and Alon (2007). Optimality for encoding additional information is particularly important and re...

2

Teleomechanist: July 2008

http://teleomechanist.blogspot.com/2008_07_01_archive.html

Musings on "teleogenomics"/"telic memetics". Saturday, July 26, 2008. Life has a genetic toolkit. To build a wide variety of forms from just a few basic, simple and elegant body plans. Take this into consideration and take a look at how stem cells become specialized. Many Paths, Few Destinations: How Stem Cells Decide What They'll Become. How does a stem cell decide what specialized identity to adopt - or simply to remain a stem cell? Enabling cells to respond to changes in their environment in a systema...

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Teleomechanist: September 2008

http://teleomechanist.blogspot.com/2008_09_01_archive.html

Musings on "teleogenomics"/"telic memetics". Sunday, September 28, 2008. Memetic Algorithms, Convergence and Pre-existing Fitness Landscapes. MAs) are search techniques used to solve problems by mimicking molecular processes of evolution including selection, recombination, mutation and inheritance. A few important aspects of MAs (Figure 1):. The fitness landscape needs to be finite. The search space of the MA is limited to the fitness landscape. Selection is based on fitness. Population of individual are.

4

Teleomechanist: Memetic Algorithms, Convergence and Pre-existing Fitness Landscapes

http://teleomechanist.blogspot.com/2008/09/memetic-algorithms-convergence-and-pre.html

Musings on "teleogenomics"/"telic memetics". Sunday, September 28, 2008. Memetic Algorithms, Convergence and Pre-existing Fitness Landscapes. MAs) are search techniques used to solve problems by mimicking molecular processes of evolution including selection, recombination, mutation and inheritance. A few important aspects of MAs (Figure 1):. The fitness landscape needs to be finite. The search space of the MA is limited to the fitness landscape. Selection is based on fitness. Population of individual are.

5

Teleomechanist: The Optimality of the Genetic Code

http://teleomechanist.blogspot.com/2008/11/optimality-of-genetic-code.html

Musings on "teleogenomics"/"telic memetics". Tuesday, November 25, 2008. The Optimality of the Genetic Code. Early Fixation of an Optimal Genetic Code. Evolution of the genetic code: partial optimization of a random code for robustness to translation error in a rugged fitness landscape. The genetic code is nearly optimal for allowing additional information within protein-coding sequences. An extension of the coevolution theory of the origin of the genetic code. Does codon bias have an evolutionary origin?

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biomolecularmachines.blogspot.com

Biomolecular Machines: Computers Making Computers?

http://biomolecularmachines.blogspot.com/2009/01/computer-making-computers.html

Thursday, January 1, 2009. An interesting article authored by Antoine Danchin from the Pasteur Institut was recently published and is sure to bring forth much discussion. Bacteria as computers making computers. The quantum teleportation experiments. Have demonstrated that information can be viewed as a fundamental irreducible property of physics ( informationalism. There are many interesting passages in this article. A few of these are going to be highlighted for discussion. Cellular processes are exquis...

biomolecularmachines.blogspot.com

Biomolecular Machines: January 2009

http://biomolecularmachines.blogspot.com/2009_01_01_archive.html

Monday, January 19, 2009. In order to demonstrate the validity of viewing cells as computers that are able to manipulate information, consider the following finding. The Ribosome: Perfectionist Protein-maker Trashes Errors. ScienceDaily (Jan. 9, 2009) — The enzyme machine that translates a cell's DNA code into the proteins of life is nothing if not an editorial perfectionist. We thought that once the mistake was made, it would have just gone on to make the next bond and the next,. Information. Materi...

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Biomolecular Machines: Protein folding, Nanotubes and Engineering

http://biomolecularmachines.blogspot.com/2008/11/protein-folding-and-engineering.html

Tuesday, November 25, 2008. Protein folding, Nanotubes and Engineering. More on protein folding:. Many proteins have intricate folds and one of these fold types include the figure eight knot. Fold A team of researchers tried to figure out how these proteins are folded. At present, it is only known that the knot is formed quickly soon after polypeptide chain formation, with an unknown mechanism. The researchers tentatively propose:. Perhaps an an as of yet undiscovered knot-folding machine? I'll bet you t...

biomolecularmachines.blogspot.com

Biomolecular Machines: December 2008

http://biomolecularmachines.blogspot.com/2008_12_01_archive.html

Friday, December 5, 2008. The Kinesin Motor Machine. How Tiny Cell Proteins Generate Force To 'Walk'. ScienceDaily (Dec. 4, 2008) — MIT researchers have shown how a cell motor protein exerts the force to move, enabling functions such as cell division. Kinesin, a motor protein that also carries neurotransmitters,. Along cellular beams known as microtubules. For the first time, the MIT team has shown at a molecular level how kinesin generates the force needed to step along the microtubules. Next, Lang's te...

biomolecularmachines.blogspot.com

Biomolecular Machines: The Kinesin Motor Machine.

http://biomolecularmachines.blogspot.com/2008/12/kinesin-motor-machine.html

Friday, December 5, 2008. The Kinesin Motor Machine. How Tiny Cell Proteins Generate Force To 'Walk'. ScienceDaily (Dec. 4, 2008) — MIT researchers have shown how a cell motor protein exerts the force to move, enabling functions such as cell division. Kinesin, a motor protein that also carries neurotransmitters,. Along cellular beams known as microtubules. For the first time, the MIT team has shown at a molecular level how kinesin generates the force needed to step along the microtubules. Next, Lang's te...

biomolecularmachines.blogspot.com

Biomolecular Machines: Replication Machinery and Transcription Factories

http://biomolecularmachines.blogspot.com/2008/11/how-dna-is-unwound-so-that-its-code-can.html

Tuesday, November 25, 2008. Replication Machinery and Transcription Factories. How DNA Is Unwound So That Its Code Can Be Read. ScienceDaily (Nov. 24, 2008) — Researchers at The Scripps Research Institute have figured out how a macromolecular machine is able to unwind the long and twisted tangles of DNA within a cell's nucleus so that genetic information can be "read" and used to direct the synthesis of proteins, which have many specific functions in the body. Remarkable Unpacking and Repacking". What th...

biomolecularmachines.blogspot.com

Biomolecular Machines: Idle Control Units and Metabolomics

http://biomolecularmachines.blogspot.com/2008/12/idle-control-units-and-metabolomics.html

Friday, December 5, 2008. Idle Control Units and Metabolomics. Well designed cars have well designed idle control units. That spontaneously kick in to maintain the speed of the crankshaft within a pre-set range (usually 200rpm). An interesting study has demonstrated that 4 single celled organisms in two domains of life (bacteria and eukaryotes) uses the same number of biochemical reactions when optimizing growth. Spontaneous Reaction Silencing in Metabolic Optimization. Glucose metabolic network can be r...

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Musings on "teleogenomics"/"telic memetics". Tuesday, September 22, 2009. Nano-intentionality and Molecular Autonomous Agents. Intrinsic intentionality and inherent goal-directedness of eukaryotic cells is defended by Tecumseh Fitch. And minimal molecular autonomous agents are characterized in " On emergence, agency, and organization. By Stuart Kauffman and Philip Clayton). The "aboutness" and "goal-directedness" of eukaryotic cells and how it relates to nano-intentionality is defined as follows (p14):.

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