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The Alpha-1 Project | What is The Alpha-1 Project?

The Alpha-1 Project (TAP) is a wholly-owned for profit subsidiary of the Alpha-1 Foundation. TAP will focus funding into highly promising drug therapies or devices in the translational research or clinical trial stage of development to speed the commercialization of these therapies.

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The Alpha-1 Project | What is The Alpha-1 Project? | thealpha-1project.com Reviews
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The Alpha-1 Project (TAP) is a wholly-owned for profit subsidiary of the Alpha-1 Foundation. TAP will focus funding into highly promising drug therapies or devices in the translational research or clinical trial stage of development to speed the commercialization of these therapies.
<META>
KEYWORDS
1 the alpha 1 project
2 mission and vision
3 alpha 1 antitrypsin deficiency
4 therapeutic strategies
5 clinical trial resources
6 progress reports
7 appendix
8 about us
9 news
10 documents
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the alpha 1 project,mission and vision,alpha 1 antitrypsin deficiency,therapeutic strategies,clinical trial resources,progress reports,appendix,about us,news,documents,why now,site,donate,learn more,latest news,general contact,privacy statement
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The Alpha-1 Project | What is The Alpha-1 Project? | thealpha-1project.com Reviews

https://thealpha-1project.com

The Alpha-1 Project (TAP) is a wholly-owned for profit subsidiary of the Alpha-1 Foundation. TAP will focus funding into highly promising drug therapies or devices in the translational research or clinical trial stage of development to speed the commercialization of these therapies.

INTERNAL PAGES

thealpha-1project.com thealpha-1project.com
1

Progress Reports | The Alpha-1 Project

http://www.thealpha-1project.com/ProgressReports.aspx

Projects, Partnerships and Funding. Scientific and Business Advisory Council. The Alpha-1 Project, the Alpha-1 Foundation’s venture philanthropy program, is designed to accelerate the process of new drug and device development and ultimately eliminate the effects of COPD and liver disease caused by Alpha-1 Antitrypsin Deficiency. COPD: New Lessons from Alpha-1 Antitrypsin Deficiency? Adam Wanner, MD. University of Miami Miller School of Medicine – Miami, FL. Alpha-1 Foundation – Miami, FL. Subsequent res...

2

Alnylam and The Alpha-1 Project (TAP) Form Collaboration for the Advancement of ALN-AAT, an RNAi Therapeutic in Development for the Treatment of Alpha-1 Antitrypsin (AAT) Deficiency- Associated Liver Disease > The Alpha 1 Project

http://www.thealpha-1project.com/AboutUs/News/tabid/84/ID/11/Alnylam-and-The-Alpha-1-Project-TAP-Form-Collaboration-for-the-Advancement-of-ALN-AAT-an-RNAi-Therapeutic-in-Development-for-the-Treatment-of-Alpha-1-Antitrypsin-AAT-Deficiency-Associated-Liver-Disease.aspx

Projects, Partnerships and Funding. Scientific and Business Advisory Council. News From The Alpha-1 Project. Alnylam and The Alpha-1 Project (TAP) Form Collaboration for the Advancement of ALN-AAT, an RNAi Therapeutic in Development for the Treatment of Alpha-1 Antitrypsin (AAT) Deficiency- Associated Liver Disease. Posted on June 20, 2014. Alnylam Remains On Track to File Investigational New Drug (IND) Application in Mid 2015 -. About Alpha-1 Antitrypsin (AAT) and AAT Deficiency. Mission statement: The ...

3

Progress Reports Appendix 1 and 2 | The Alpha-1 Project

http://www.thealpha-1project.com/ProgressReports/Appendix.aspx

Projects, Partnerships and Funding. Scientific and Business Advisory Council. Alpha-1 Related Publications by A1F Funded Investigators. Alpha-1 Antitrypsin replacement therapy: current status. Current Opinions in Pulmonary Medicine. Neutrophil elastase cleaves Laminin-332 (laminin-5) generating peptides that are chemotactic for neutrophils. Journal of Biological Chemistry. Journal of Biological Chemistry. Journal of Biological Chemistry. Journal of Pediatric Gastroenterology. The Journal of Immunology.

4

Arrowhead Announces New Clinical Candidate ARC-AAT for Treatment of Alpha-1 Antitrypsin Deficiency-Associated Liver Disease > The Alpha 1 Project

http://www.thealpha-1project.com/AboutUs/News/tabid/84/ID/12/Arrowhead-Announces-New-Clinical-Candidate-ARC-AAT-for-Treatment-of-Alpha-1-Antitrypsin-Deficiency-Associated-Liver-Disease.aspx

Projects, Partnerships and Funding. Scientific and Business Advisory Council. News From The Alpha-1 Project. Arrowhead Announces New Clinical Candidate ARC-AAT for Treatment of Alpha-1 Antitrypsin Deficiency-Associated Liver Disease. Posted on June 20, 2014. RNAi Therapeutic ARC-AAT Induces Dose Dependent Reductions in Mutant AAT Protein of Greater than 95 Percent in. Long Duration of Effect with AAT Remaining Reduced by More than 80% at 6 Weeks after a Single Dose. AATD is one of the most common genetic...

5

Clinical Trial Resources | The Alpha-1 Project

http://www.thealpha-1project.com/ClinicalTrialResources.aspx

Projects, Partnerships and Funding. Scientific and Business Advisory Council. The Alpha-1 Project provides access to individuals with Alpha-1 willing to participate in clinical trials through the following Alpha-1 Foundation programs. Alpha-1 Research Registry Program at the Medical University of South Carolina. The Registry is conducted under the direction of Charlie Strange, M.D. at the Medical University of South Carolina. For more information about the Registry Program, you may visit the ...The bank,...

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alnylam.com alnylam.com

Strategic Alliances – Alnylam

http://www.alnylam.com/our-approach/strategic-alliances

Delivery of RNAi Therapeutics. Hereditary ATTR Amyloidosis with Polyneuropathy (hATTR-PN). Hereditary ATTR Amyloidosis with Cardiomyopathy (hATTR-CM). Access to Investigational Drugs. Free Third-Party Generic Screening and Counseling Programs. Patient Connect E-Mail Alert Sign Up. Access to Investigational Drugs. Delivery of RNAi Therapeutics. Genetic Medicine Strategic Therapeutic Area (STAr). Hereditary ATTR Amyloidosis with Polyneuropathy (hATTR-PN). The venture philanthropy subsidiary of the Alpha-1 ...

inhibrx.com inhibrx.com

Alpha-1 Disease - InhibRx

http://inhibrx.com/therapeutic-areas/aat-deficiency

Inhibrx’s AAT-Fc has the potential to benefit Alpha-1 Disease patients through improved efficacy and less frequency dosing. This therapeutic is supported by the Alpha-1 Project and is expected to initiate clinical studies in 2017. Inhibrx’s AAT-Fc therapeutic is manufactured in mammalian cells, the industry standard for commercial therapeutic antibody and Fc fusion protein production. Cell line development data indicate this therapeutic is a high yielding protein that is easily scalable and will have...

imisoftwareinc.com imisoftwareinc.com

Web Design Portfolio | DotNetNuke | IMI Software, Inc.

http://www.imisoftwareinc.com/Portfolio.aspx

Learn About Our Author Web Solutions. Learn About Our Author Web Solutions. Have a look at some of our work. In partnership with R2integrated. Benfield Electric, Inc. Telemachus Press, LLC. In partnership with R2integrated. DeThomas and Son Concrete. Sycee Capital, LLC. The Beaver Bat Company. Walt Siefert Real Estate. The COPD Foundation is hosting the COPD8USA Conference June 14-15, 2013 in Chicago, Illinois. The Beaver Bat Company. The Beaver Bat Company. Telemachus Press, LLC. Telemachus Press, LLC.

alnylam.com alnylam.com

Alpha-1 Antitrypsin Deficiency – Alnylam

http://www.alnylam.com/product-pipeline/alpha-1-antitrypsin-deficiency

Delivery of RNAi Therapeutics. Hereditary ATTR Amyloidosis with Polyneuropathy (hATTR-PN). Hereditary ATTR Amyloidosis with Cardiomyopathy (hATTR-CM). Access to Investigational Drugs. Free Third-Party Generic Screening and Counseling Programs. Patient Connect E-Mail Alert Sign Up. Access to Investigational Drugs. Delivery of RNAi Therapeutics. Genetic Medicine Strategic Therapeutic Area (STAr). Hereditary ATTR Amyloidosis with Polyneuropathy (hATTR-PN). In May 2015, we filed a Clinical Trial Application ...

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SUBSCRIBE TO THE FEED. Alpha-1 All The Time! The Alpha-1 Foundation is dedicated to providing the leadership and resources that will result in increased research, improved health, worldwide detection, and a cure for Alpha-1 Antitrypsin Deficiency. Q: What is Alpha-1? A: A hereditary condition which can cause lung disease in adults and liver disease in people of all ages. Alphas and carriers, now's the chance to be heard. Posted on 9:06 AM. Or 1-888-825-7421, Ext. 217. Posted on 11:23 AM. He was remembere...

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Projects, Partnerships and Funding. Scientific and Business Advisory Council. What is The Alpha-1 Project? The Alpha-1 Project (TAP) is a wholly-owned for profit subsidiary of the Alpha-1 Foundation. Singularly focused on providing critical funding and advice to speed the commercialization of therapies for the elimination of Chronic Obstructive Pulmonary Disease (COPD) and liver disease caused by Alpha-1 Antitrypsin Deficiency (Alpha-1). Our Scientific and Business Advisory Council. Has identified novel ...

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