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TissueNetix Cellular Networks by Design

Cellular Networks by Design (CND ). The new standard for pre-clinical drug toxicity and metabolism screening. Patent protected, 2- dimensional mini-tissue mimics human organs. Cardiac, smooth muscle, neuronal tissue assay platforms. Consistent, scalable stem cell/tissue sourcing ensures reliable standard. Cardio Verification Test (CardioVT) ). Assays; Fee for Service, Kits. Networked cells, human source mimics actual cardiac tissue behavior. Unexpected cardiac toxicity a major, costly barrier.

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TissueNetix Cellular Networks by Design | tissuenetix.com Reviews
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Cellular Networks by Design (CND ). The new standard for pre-clinical drug toxicity and metabolism screening. Patent protected, 2- dimensional mini-tissue mimics human organs. Cardiac, smooth muscle, neuronal tissue assay platforms. Consistent, scalable stem cell/tissue sourcing ensures reliable standard. Cardio Verification Test (CardioVT) ). Assays; Fee for Service, Kits. Networked cells, human source mimics actual cardiac tissue behavior. Unexpected cardiac toxicity a major, costly barrier.
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TissueNetix Cellular Networks by Design | tissuenetix.com Reviews

https://tissuenetix.com

Cellular Networks by Design (CND ). The new standard for pre-clinical drug toxicity and metabolism screening. Patent protected, 2- dimensional mini-tissue mimics human organs. Cardiac, smooth muscle, neuronal tissue assay platforms. Consistent, scalable stem cell/tissue sourcing ensures reliable standard. Cardio Verification Test (CardioVT) ). Assays; Fee for Service, Kits. Networked cells, human source mimics actual cardiac tissue behavior. Unexpected cardiac toxicity a major, costly barrier.

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1

Cardiotoxicity

http://www.tissuenetix.com/cardiotoxicity.html

Inconsistent Cardiotoxicity Screening Process. The current cardiotoxicity assay does not accurately predict human cardiac toxicities. Some drugs do not get picked up by this assay, but do cause cardiac toxicity in humans. Other drugs fail in this assay but cause no cardiac side effects in humans. This could prevent the introduction of major new therapies. The FDA is considering new safety screening tools. Cardio Verification Test (CardioVT ). 96-well format (fits in standard workflows).

2

About Us

http://www.tissuenetix.com/about-us.html

About TissueNetix, Inc. Human induced pluripotent stem cell (iPSC)-derived cardiomyocytes have offered major advantages in detecting drug cardiotoxicity. These cells not only retain cardiac features but are durable in cell culture environments for laboratory experiments. Currently, iPSC-derived cardiomyocytes can be purchased in a cell culture format; however, such disorganized arrays fall short in providing scientists with an accurate simulacrum of the heart. New Company Formed for Development of new ca...

3

CND

http://www.tissuenetix.com/cnd.html

The pressure to create safe, targeted and effective ethical drugs within the pharmaceutical industry has never been higher. Current toxicology assays often use rodent cell models, which offer poor predictive value. U.S. regulatory agencies have been clear that a more effective model is needed to predict drug response and toxicity. A few recent publications are shown here:. Nobel Prize-Winner’s Stem Cells Help Glaxo Pinpoint Risks. Speedy validation sought for new cardiotoxicity testing strategy.

4

News/Press Releases

http://www.tissuenetix.com/News/Press-Releases

New Company Formed for Development of new cardiac toxicity assays. Read more: New Company Formed. 11011 Torreyana Rd, Suite 150, San Diego CA 92121, (858) 204-9243, info@tissuenetix.com.

5

Our Team

http://www.tissuenetix.com/board-of-directors.html

David Giegel, Ph.D. Founder, CSO and President, TissueNetix, Inc. Owner, Hara CPA Professional Services, Inc. Chief Financial Officer and Member, Board of Directors, TissueNetix, Inc. Lewis Shuster, M.B. A. Chief Executive Officer, Shuster Capital. Founder and Executive Chairman, TissueNetix, Inc. Roberta Gottlieb, M.D. Director of Molecular Cardiobiology, Cedars-Sinai Medical Center. Founder, TissueNetix, Inc. David Webb, Ph.D. Chairman, Sorrento Therapeutics. Advisor, TissueNetix, Inc.

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