TP53.org is a site dedicated to bringing basic, advanced and current information on the TP53 gene, p53 protein and there significance. p53 has revolutionized our understanding of the molecular biology of cancer, cancer initiation and cancer progression. The p53 gene is altered in more than half of all cancers, and its dysfunction is associated with more aggressive cancers and a worse prognosis.
http://www.tp53.org/
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TP53 | tp53.org Reviews
https://tp53.org
TP53.org is a site dedicated to bringing basic, advanced and current information on the TP53 gene, p53 protein and there significance. p53 has revolutionized our understanding of the molecular biology of cancer, cancer initiation and cancer progression. The p53 gene is altered in more than half of all cancers, and its dysfunction is associated with more aggressive cancers and a worse prognosis.
tp53.org
p53 Protein
http://www.tp53.org/p53-protein
TP53 and p53 Links. P53, Protein 53, Tumor Protein 53, Cellular Tumor Antigen p53. P53 is a transcription factor, also known as protein 53 or tumor protein 53 or cellular tumor antigen p53. The TP53 gene. On chromosome 17 encodes p53. P53 Name and Molecular Mass. Called p53 due to its molecular mass of 53 kilodaltons, 53 kDa, when run on SDS-PAGE. Actual weight should be around 44 kDa, but runs slower on SDS-PAGE due to high number of proline residues. Nuclea localization signaling domain. Cell stresses ...
TP53
http://www.tp53.org/tp53-gene
TP53 and p53 Links. TP53 is the gene that encodes for p53. Known as tumor antigen 53 or protein 53. TP53 is located on chromosome 17p13.1, short arm, in humans. TP53 is on different locations in other species. Dog chromosome 5, Rat chromosome 10, Mouse, chromosome 11, Pig chromosome 12. P53 Gene and Protein CUSTOM SEARCH.
p53 Mutation
http://www.tp53.org/p53-mutation
TP53 and p53 Links. P53 Mutations are criticial events in the progression to cellular dysfunction and carcinogenesis through cell cycle control loss. Majority of p53 mutations occur in the DNA-binding core domain (DBD). DBD mutations prevent p53 from binding DNA and acting transcription factors. These are termed recessive loss of function mutations. Mutations, have a dominant nevative effect, as the abnormal p53 binds normal p53, unabling transcription activation. P53 Mutations in Human Cancers. Patients...
p53 Structure
http://www.tp53.org/p53-structure
TP53 and p53 Links. N-terminal domain, resides 1-42, is an activation domain (AD1, also termed transcription-activation domain, TAD). Activation domain 1 activates transcription factors. Activation domain 2 (AD2), residues 43-63, is for apoptosis activation. Proline rich domain, which gives p53 its characteristic molecular mass, residues 80-94, is for apoptosis. DNA-binding core domain (DBD), residues 100-300, is located centrally. Nuclear localization signaling domain, residues 316-325.
p53 pathways
http://www.tp53.org/p53-pathways
TP53 and p53 Links. P53 and apoptosis, flow diagram depicting crucial entry points of regulation in addition to actions carried out by similar proteins and the apoptotic cascade. P53 Gene and Protein CUSTOM SEARCH.
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TP52 MATADOR
Martes, 23 de octubre de 2007. Lunes, 8 de octubre de 2007. Hola a Todos nuevamente;. La ultima actualizacion del blog fue despues del 1er evento de la Med Cup 07 en ALICANTE en junio pasado donde comenzo a rodar esta historia del MATADOR / SIEMENS en la clase TP52. RESULTADOS DE LA TEMPORADA 2007:. 8vos TROFEO de ALICANTE 1er Evento Med Cup 2007. 4to Trofeo SAR La Reina, Valencia (no-MedCup). 3ro Trofeo BREITLING Pto. Portals Palma de Mallorca (2do Evento MedCup 2007). Un balance positivo de esta tempor...
Introduction
The George Pantziarka TP53 Trust. Helping families with Li Fraumeni Syndrome and other TP53 disorders. Towards A TP53 Registry. Interview With Galina Selivanova. Having discussed the issue with a number of doctors and researchers, we have decided to create the George Pantziarka TP53 Trust. In George's memory. The aim is to provide support to families and individuals, to provide information to all, and to help foster understanding and research into the condition. LFS - Primed for cancer - Interview. The e...
TP53
TP53 and p53 Links. Your source for information on TP53 gene, p53 protein and TP53 p53 research. TP53 and p53 Molecular Research. Other names p53 is known by: p53, p53 protein, tumor antigen p53, tumor suppressor p53, antigen NY-CO-13, phosphoprotein p53, and TRP53 (transformation-related protein 53). TP53 gene and p53 Protein. P53 Gene and Protein CUSTOM SEARCH.
Introduction
The George Pantziarka TP53 Trust. Helping families with Li Fraumeni Syndrome and other TP53 disorders. Towards A TP53 Registry. Interview With Galina Selivanova. Having discussed the issue with a number of doctors and researchers, we have decided to create the George Pantziarka TP53 Trust. In George's memory. The aim is to provide support to families and individuals, to provide information to all, and to help foster understanding and research into the condition. LFS - Primed for cancer - Interview. The e...
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