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Has been used as an analgesic since the late 1970s, and became one of the most popular analgesics of its class in Germany. International interest for the drug has been renewed when it was discovered that tramadol not only acts like opioids, but also inhibits serotonin and noradrenaline reuptake. Tramadol is generally well tolerated, the most common side effects being nausea and vomiting. In contrast to agents such as morphine and pethidine, respiratory depression rarely occurs during tramadol treatme...
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