TRANSGENIC-HYDRA.ORG

www.transgenic-hydra.org

The Transgenic Hydra Facility is a non-profit facility in the laboratory of Thomas Bosch at the University of Kiel that assists scientists to use and to develop transgenic Hydra polyps. Our mission is to provide investigators access to the latest technology for the efficient production of transgenic polyps. We particularly encourage scientists from laboratories lacking the infrastructure for transgenic Hydra technologies to use our services.

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Zoologisches Institut, Abt. Bosch, Universitaet Kiel

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The Transgenic Hydra Facility is a non-profit facility in the laboratory of Thomas Bosch at the University of Kiel that assists scientists to use and to develop transgenic Hydra polyps. Our mission is to provide investigators access to the latest technology for the efficient production of transgenic polyps. We particularly encourage scientists from laboratories lacking the infrastructure for transgenic Hydra technologies to use our services.

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www.transgenic-hydra.org | transgenic-hydra.org Reviews

https://transgenic-hydra.org

The Transgenic Hydra Facility is a non-profit facility in the laboratory of Thomas Bosch at the University of Kiel that assists scientists to use and to develop transgenic Hydra polyps. Our mission is to provide investigators access to the latest technology for the efficient production of transgenic polyps. We particularly encourage scientists from laboratories lacking the infrastructure for transgenic Hydra technologies to use our services.

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transgenic-hydra.org

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www.transgenic-hydra.org

http://www.transgenic-hydra.org/lines.htm

Introduction to existing transgenic Hydra lines:. The tissue of adult Hydra is transparent allowing the visualization of individual cells by means of GFP fluorescence and facilitating in vivo tracking of cells within the intact organism. We have successfully established a number of transgenic Hydra vulgaris (strain AEP) lines which stably express eGFP in either the endodermal or ectodermal epithelial stem cells or the interstitial cell lineage. Available transgenic Hydra lines:.

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www.transgenic-hydra.org

http://www.transgenic-hydra.org/services.htm

Production of new transgenic Hydra via embryo microinjection:. The introduction of foreign DNA (transgenes) into the genome of Hydra allows studies of gene expression and protein function within live polyps. The Transgenic Hydra Facility at Kiel University offers the opportunity to produce such transgenic polyps. Essentially the steps necessary for the production of transgenic polyps are:. 2 Purification of the transgene for microinjection. Purification of Transgene for Microinjection:. Highly purified D...

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www.transgenic-hydra.org

http://www.transgenic-hydra.org/index.htm

The Transgenic Hydra Facility is a non-profit facility in the laboratory of Thomas Bosch at the University of Kiel that assists scientists to use and to develop transgenic Hydra polyps. Our mission is to provide investigators access to the latest technology for the efficient production of transgenic polyps. We particularly encourage scientists from laboratories lacking the infrastructure for transgenic Hydra technologies to use our services.

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www.transgenic-hydra.org

http://www.transgenic-hydra.org/links.htm

A synthetic RFP-gene for Hydra. A comparative genomics platform for basal metazoa.

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http://www.transgenic-hydra.org/publications.htm

Boehm AM, G Hemmrich, K Khalturin, M Puchert, F Anton-Erxleben, J Wittlieb, UC Klostermeier, P Rosenstiel, H-H Oberg, and TCG Bosch (2012) FoxO is a critical regulator of stem cell maintenance and immortality in Hydra. Proc Natl Acad Sci USA, 109(48):19697-702. Franzenburg S, S Fraune, S Künzel, JF Baines, T Domazet-Lošo, TCG Bosch (2012) MyD88 deficient Hydra reveal ancient function of TLR-signaling in sensing bacterial colonizers. Proc Natl Acad Sci USA 109 (47): 19374-9. Wittlieb J, K Khalturin, TCG B...

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transgenic-hydra.org

www.transgenic-hydra.org

The Transgenic Hydra Facility is a non-profit facility in the laboratory of Thomas Bosch at the University of Kiel that assists scientists to use and to develop transgenic Hydra polyps. Our mission is to provide investigators access to the latest technology for the efficient production of transgenic polyps. We particularly encourage scientists from laboratories lacking the infrastructure for transgenic Hydra technologies to use our services.

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