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Creating Next Generation TNF Antagonists. Our goal is to develop more effective and convenient anti-TNF-α antibodies for autoimmune disorders. Trimer Biotech acquired clinical stage (AME-527) and preclinical stage anti-TNF-α antibodies from Eli Lilly and Company in May 2012. In Phase I/II clinical trials, AME-527 demonstrated a high response rate (ACR20 of 94%) in patients with rheumatoid arthritis (RA) who failed at least 1 DMARD (disease modifying antirheumatic drugs). Subcutaneous administration of hu...

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Creating Next Generation TNF Antagonists. Our goal is to develop more effective and convenient anti-TNF-α antibodies for autoimmune disorders. Trimer Biotech acquired clinical stage (AME-527) and preclinical stage anti-TNF-α antibodies from Eli Lilly and Company in May 2012. In Phase I/II clinical trials, AME-527 demonstrated a high response rate (ACR20 of 94%) in patients with rheumatoid arthritis (RA) who failed at least 1 DMARD (disease modifying antirheumatic drugs). Subcutaneous administration of hu...

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3 pipeline

4 research

5 careers

6 career opportunities

7 efficacy

8 safety

9 indications

10 rheumatology

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Trimer Bio Homepage | trimerbio.com Reviews

https://trimerbio.com

Creating Next Generation TNF Antagonists. Our goal is to develop more effective and convenient anti-TNF-α antibodies for autoimmune disorders. Trimer Biotech acquired clinical stage (AME-527) and preclinical stage anti-TNF-α antibodies from Eli Lilly and Company in May 2012. In Phase I/II clinical trials, AME-527 demonstrated a high response rate (ACR20 of 94%) in patients with rheumatoid arthritis (RA) who failed at least 1 DMARD (disease modifying antirheumatic drugs). Subcutaneous administration of hu...

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trimerbio.com

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Mentrik Homepage

http://www.trimerbio.com/careers.html

Creating Next Generation TNF Antagonists. Mentrik offers exciting opportunities for candidates in a fast-based start-up company led by highly successful entrepreneurs. Individuals with a science background are preferred for available positions. Candidates must be hard working and effective team players. We are currently recruiting for:. CMC and Regulatory Specialist. Experimental scientist with background in genetic engineering, immunology and IND-enabling preclinical studies in animal models.

2

Mentrik Homepage

http://www.trimerbio.com/pipeline.html

Creating Next Generation TNF Antagonists. In a mouse model which recapitulates the symptoms of human rheumatoid arthritis, these improvements translate into significantly higher potency, as measured by the prevention of joint swelling and disease progression. AME-532 has a higher affinity for TNF-α. AME-532 is currently in preclinical development. Trimer Biotech, LLC. Info@trimer.com (214) 593 0500. 5420 LBJ Freeway, Suite 410, Dallas, TX 75240.

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Mentrik Homepage

http://www.trimerbio.com/news.html

Creating Next Generation TNF Antagonists. May 02, 2012. TRIMER Biotech, LLC is pleased to announce the successful acquisition of AME-527, an anti-TNF-α monoclonal antibody under development for autoimmune disorders. AME-527 is a subcutaneously administered, fully humanized, high-affinity monoclonal antibody for which Phase I/II clinical development has been completed in patients with rheumatoid arthritis (RA) who failed at least 1 DMARD (disease modifying antirheumatic drugs). List of New Items.

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Trimer Bio Homepage

http://www.trimerbio.com/home.html

Creating Next Generation TNF Antagonists. Our goal is to develop more effective and convenient anti-TNF-α antibodies for autoimmune disorders. Trimer Biotech acquired clinical stage (AME-527) and preclinical stage anti-TNF-α antibodies from Eli Lilly and Company in May 2012. In Phase I/II clinical trials, AME-527 demonstrated a high response rate (ACR20 of 94%) in patients with rheumatoid arthritis (RA) who failed at least 1 DMARD (disease modifying antirheumatic drugs). Subcutaneous administration of hu...

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Creating Next Generation TNF Antagonists. Our goal is to develop more effective and convenient anti-TNF-α antibodies for autoimmune disorders. Trimer Biotech acquired clinical stage (AME-527) and preclinical stage anti-TNF-α antibodies from Eli Lilly and Company in May 2012. In Phase I/II clinical trials, AME-527 demonstrated a high response rate (ACR20 of 94%) in patients with rheumatoid arthritis (RA) who failed at least 1 DMARD (disease modifying antirheumatic drugs). Subcutaneous administration of hu...

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