biocascades.eu
Workpackage 2: Enantiopure 1,3/1,4-amino acids and amino alcohols from prochiral ketoacids | Biocascades
http://www.biocascades.eu/project/workpackages/workpackage-2
The Early Stage Researchers. KTH Royal Institute of Technology. Workpackage 2: Enantiopure 1,3/1,4-amino acids and amino alcohols from prochiral ketoacids. June 26, 2015. July 20, 2015. Jun-Prof. Dr. Robert Kourist. Entrechem, SARomics, DSM, Viazym. Description of work and role of partners. 1) Avoiding cross-reactivity by flow-chemistry. 2) Generation of a broad-spectrum amino acid decarboxylase by protein engineering. 3) Proof-of-principle of a new three-enzyme cascade with in situ cofactor generation.
biocascades.eu
Workpackage 3: Transaminase-catalyzed multi-enzyme cascade reactions | Biocascades
http://www.biocascades.eu/project/workpackages/workpackage-3
The Early Stage Researchers. KTH Royal Institute of Technology. Workpackage 3: Transaminase-catalyzed multi-enzyme cascade reactions. June 26, 2015. July 20, 2015. Jun-Prof. Dr. Matthias Höhne. Entrechem, SARomics, Enzymicals, KTH, Viazym. Description of work and role of partners. Novel equilibrium shift strategies: ESR 6 investigates novel achiral amine-donors, such as α,ω-diamines, (NH2-(CH2)n-NH2; n=2-5) and ω-aminoalkan-1-ols (NH2-(CH2)n-NH2; n=4-5) and the oxidation of the formed hemiacetal byproduc...
biocascades.eu
Workpackage 5: Management | Biocascades
http://www.biocascades.eu/project/workpackages/workpackage-5
The Early Stage Researchers. KTH Royal Institute of Technology. July 9, 2015. July 20, 2015. Jun-Prof. Robert Kourist. Tasks of the Management Team. The primary responsibilities for the coordinator are:. Monitoring overall implementation of the Project. Acting as primary contact for the EU Project Officer. Chairing Meetings of the steering committee. Submitting reports and deliverables to the EU Project Officer. Submitting cost claims and audit certificates. Receiving and distributing payments from the EC.
biocascades.eu
Workpackage 4: Transaminase tandem reactions employing metal and organo catalysts | Biocascades
http://www.biocascades.eu/project/workpackages/workpackage-4
The Early Stage Researchers. KTH Royal Institute of Technology. Workpackage 4: Transaminase tandem reactions employing metal and organo catalysts. July 9, 2015. July 20, 2015. Prof Dr. Harald Gröger. Entrechem, DSM, KTH, TU Graz. Description of work and role of partners. 1) Establishment of Pd catalyzed reactions with transaminase catalysis as a new synthetic concept. 2) Up-scaling of an established cascade (TRL4) for capsaicine synthesis.
biocascades.eu
Workpackage 1: Enantiopure 1,2-aminoalcohols from achiral substrates | Biocascades
http://www.biocascades.eu/project/workpackages/workpackage-1
The Early Stage Researchers. KTH Royal Institute of Technology. Workpackage 1: Enantiopure 1,2-aminoalcohols from achiral substrates. June 18, 2015. July 20, 2015. Prof Dr. Anett Schallmey. Enzymicals, Viazym, TU Delft. Description of work and role of partners. 1) Assembly of novel two-enzyme cascades in combination with a chemical catalyst. 2) Avoiding catalyst incompatibility by micro-compartimentalization.
biocascades.eu
The Early Stage Researchers | Biocascades
http://www.biocascades.eu/training-program/esrs
The Early Stage Researchers. KTH Royal Institute of Technology. Laura Leemans a.k.a. ESR1 Department of Biotechnology Section BOC Julianalaan 136 2628 BL Delft The Netherlands Project title: Synthesis of … Read More. Gaurav Dutta Dwivedi a.k.a. ESR2 Enzymicals AG Walther-Rathenau-Straße 49a 17489 Greifswald Germany Project title: Synthesis of enantiopure 1,2-aminoalcohols from α-haloketones … Read More. Federica Ruggieri a.k.a. ESR8 SARomics Biostructures AB Medicon Village SE-223 81 Lund Swe...Lisa Marx...
biocascades.eu
Workpackages | Biocascades
http://www.biocascades.eu/project/workpackages
The Early Stage Researchers. KTH Royal Institute of Technology. Workpackage 1: Enantiopure 1,2-aminoalcohols from achiral substrates. June 18, 2015. Workpackage 2: Enantiopure 1,3/1,4-amino acids and amino alcohols from prochiral ketoacids. June 26, 2015. Workpackage 3: Transaminase-catalyzed multi-enzyme cascade reactions. June 26, 2015. Workpackage 4: Transaminase tandem reactions employing metal and organo catalysts. July 9, 2015. July 9, 2015. July 9, 2015.
biocascades.eu
The Project | Biocascades
http://www.biocascades.eu/project
The Early Stage Researchers. KTH Royal Institute of Technology. About the Biocascades Project. The Science and Technology Objectives. 1) To combine different well established enzymes and chemical catalysts in an innovative way to design novel cascades. Aim is the development of a catalytic platform for the synthesis of highly functionalized optically pure amines and 1,2-, 1,3- and 1,4-amino alcohols. 5) To develop strategies for the scale-up of viable (chemo)enzymatic cascade reactions. Develop novel enz...
biocascades.eu
Workpackage 6: Training | Biocascades
http://www.biocascades.eu/project/workpackages/workpackage-6
The Early Stage Researchers. KTH Royal Institute of Technology. July 9, 2015. July 20, 2015. Prof Dr. Anett Schallmey. Description of the Training Workpackage. Prof Anett Schallmey is the training manager. She is supported by the Project Manager. Entrepreneurial seminars at the host institutions provide transferable skills. Training events complement training in graduate schools. A ring lecture provides research-related background for the ESRs.