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Pololike kinase 3 resides in the nucleolus of mammalian cells. Cell nuclei are shown here in Blue (DAPI), The nucleolar protein fibrillarin is green. Pololike kinase 3 is red. Inset, a single nucleolus. Pericentrin is required for normal mitotic spindle formation. Cells which do not express detectable levels of pericentrin following treatment with siRNA fail to form spindles in mitosis (asterisks). Arrow- cell which expresses near normal levels of pericentrin at the centrosome. Google Start Page Links.

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Pololike kinase 3 resides in the nucleolus of mammalian cells. Cell nuclei are shown here in Blue (DAPI), The nucleolar protein fibrillarin is green. Pololike kinase 3 is red. Inset, a single nucleolus. Pericentrin is required for normal mitotic spindle formation. Cells which do not express detectable levels of pericentrin following treatment with siRNA fail to form spindles in mitosis (asterisks). Arrow- cell which expresses near normal levels of pericentrin at the centrosome. Google Start Page Links.
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Pololike kinase 3 resides in the nucleolus of mammalian cells. Cell nuclei are shown here in Blue (DAPI), The nucleolar protein fibrillarin is green. Pololike kinase 3 is red. Inset, a single nucleolus. Pericentrin is required for normal mitotic spindle formation. Cells which do not express detectable levels of pericentrin following treatment with siRNA fail to form spindles in mitosis (asterisks). Arrow- cell which expresses near normal levels of pericentrin at the centrosome. Google Start Page Links.

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Oct 14, 2010, 9:50 AM. Wendy Zimmerman edited Email Page Untitled. Jan 1, 2010, 10:57 AM. Wendy Zimmerman edited experience. Jan 1, 2010, 10:55 AM. Wendy Zimmerman edited publications. Jan 1, 2010, 10:55 AM. Wendy Zimmerman edited Email Page Untitled.

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Lee, K.S., Park, J., Kang, Y.H., Zimmerman, W., Soung, N., Seong,Y., Kwak, S., and Erikson, R.L., 2008. Mechanisms of mammalian polo-like kinase 1, (Plk1) localization: Self- versus non-self-priming. Cell Cycle: 7(2):141-145. Zimmerman, W.C. and Erikson, R.L., 2007. Finding Plk3. Cell Cycle 6(11): 1314-1318. Zimmerman, W.C. and Erikson, R.L., 2007. Polo-like kinase 3 is required for entry into S phase. PNAS 104(6): 1847-1852. Zimmerman, W.C., Sparks, S.A., and Doxsey, S.J., 1999&#...Dictenberg J.B&#4...

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patents - www

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12/99 U.S. Patent # 05998197. 12/98 U.S. Patent # 05853537. 12/97 U.S. Patent # 05695975. 4/97 U.S. Patent # 05607855. 3/97 U.S. Patent # 05609724. 12/95 U.S. Patent # 05476789.

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experience - www

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Cambridge, Massachusetts, 2004-present. Postdoctoral Fellow in the lab of Professor Raymond Erikson, 2004-present. Research designed to elucidate the signal transduction pathways and roles of polo-like kinases in the mammalian cell cycle. Current project The Function of Plk3. Identified Polo-like kinase 3 as an essential regulator of the G1-S phase transition of the cell cycle, and as a regulator of abscission. Identified cyclin E as a down-stream target of Polo-like kinase 3. Worcester, MA 1996-2004.

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Steven popkes - family tree. The important stuff for me is on the first page. Wendy is the smart one of the pair of us. I married a doctor. Dr. Zimmerman has a Masters in Microbiology and a Ph.D. of Biochemistry and Microbiology. She's doing research in the biochemistry of the cell cycle. We also call her the Pastry Queen.

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Pololike kinase 3 resides in the nucleolus of mammalian cells. Cell nuclei are shown here in Blue (DAPI), The nucleolar protein fibrillarin is green. Pololike kinase 3 is red. Inset, a single nucleolus. Pericentrin is required for normal mitotic spindle formation. Cells which do not express detectable levels of pericentrin following treatment with siRNA fail to form spindles in mitosis (asterisks). Arrow- cell which expresses near normal levels of pericentrin at the centrosome. Google Start Page Links.

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