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2015 Physical and Structural Pharmacology

Jan - Mar, 2015. The UCSD Skaggs School of Pharmacy and Pharmaceutical Sciences. Understand the underlying quantitative laws and principles governing the behavior of therapeutic agents. Understand the relationship between chemical structure of an active ingredient and its poly-pharmacology and adverse effects. News, Message Board. Final: Results. Part1. Final: Results. Part2. The overall ranking is being computed. There will be an opportunity to retake the exam. Calculators are allowed at exams and tests.

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2015 Physical and Structural Pharmacology | xablab.ucsd.edu Reviews
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Jan - Mar, 2015. The UCSD Skaggs School of Pharmacy and Pharmaceutical Sciences. Understand the underlying quantitative laws and principles governing the behavior of therapeutic agents. Understand the relationship between chemical structure of an active ingredient and its poly-pharmacology and adverse effects. News, Message Board. Final: Results. Part1. Final: Results. Part2. The overall ranking is being computed. There will be an opportunity to retake the exam. Calculators are allowed at exams and tests.
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2 ruben abagyan
3 objectives and
4 the equation sheet
5 supplementary information
6 projects
7 schedule
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2015 Physical and Structural Pharmacology | xablab.ucsd.edu Reviews

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Jan - Mar, 2015. The UCSD Skaggs School of Pharmacy and Pharmaceutical Sciences. Understand the underlying quantitative laws and principles governing the behavior of therapeutic agents. Understand the relationship between chemical structure of an active ingredient and its poly-pharmacology and adverse effects. News, Message Board. Final: Results. Part1. Final: Results. Part2. The overall ranking is being computed. There will be an opportunity to retake the exam. Calculators are allowed at exams and tests.

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2015 Drug Mechanism projects

http://xablab.ucsd.edu/15/pj.html

2015 Drug Mechanism Projects. Friday, March 6, Day 1. 9am. Aspirin and Dicolfenac, Cyclooxygenase and more. Aspirin-like compound with PGH2. Hormones and Nuclear Receptors. Testosterone with AR and SHBG ( lamin A). DHT in pocket image. Hormonal contraception: Progesterone and Estradiol,. Estradiol : Estrogen Receptor. Levonorgestrel : Progesterone Receptor. Dexamethasone Glucocorticoid Receptor Agonist and more. Dexamethasone in GR off target table. GPCRs and Channel Modulators. Sitagliptin: PDD4 and more.

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2015 Physical and Structural Pharmacology. Appendices

http://xablab.ucsd.edu/rev.html

Physical Chemistry of Drugs. Summary. This document contains statements, formulae, units and data tables which you are supposed to know. Return to the main page. Understand the underlying quantitative principles governing the behavior of therapeutic agents including:. Stability and storage of a therapeutic formulation,. Dissolution of drug crystals and powders and crystallization of drug metabolites. Protonation and deprotonation, acid-base equilibrium and its role in permeability and solubility. Small m...

3

2013 Physical and Structural Pharmacology. Appendices

http://xablab.ucsd.edu/eqs.html

Mole, Avogadro (6): N. 6022 • 10. Length of a C-C single bond: 1.5&Aring (from 1.2 to 1.54). Kinetic energy = mv. Energy units: J ≡ kg m. 1 cal = 4.184 J; Cal = kcal;. 1eV = 1.6 10. J (corresponds to 1240 nm). E=mc. C ≈ 3*10. M/s , E= hf. 1 eV of one particle translates into ≈ 100 kJ of N. Force, Newton’s 2nd law, F. Units: N ≡ kg m s. Celsius /Kelvin conversion K = 273.15 C. 8314 J/(K•mol) 1.986 (≈2) cal/(K•mol) ; 0.08205746 L atm / (K mol) ; 5.189 10. RT at room temp = 0.6 kcal/mol or 2.5 kJ/mol. Estim...

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2015 Physical and Structural Pharmacology

Jan - Mar, 2015. The UCSD Skaggs School of Pharmacy and Pharmaceutical Sciences. Understand the underlying quantitative laws and principles governing the behavior of therapeutic agents. Understand the relationship between chemical structure of an active ingredient and its poly-pharmacology and adverse effects. News, Message Board. Final: Results. Part1. Final: Results. Part2. The overall ranking is being computed. There will be an opportunity to retake the exam. Calculators are allowed at exams and tests.

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