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Skip to main content. See How XELJANZ Works Video. Discovery of XELJANZ Video. Small Molecule, Oral Delivery. Access and Support Forms. This site is intended for US Healthcare Professionals. See How XELJANZ Works Video. Discovery of XELJANZ Video. Small Molecule, Oral Delivery. Access and Support Forms. Register on PfizerPro for the latest information. Do your patients want. From their RA treatment? A New class,. Works differently from biologics. XELJANZ is a JAK inhibitor that reduces. N Engl J Med.
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Risk Evaluation and Mitigation Strategy (REMS). A Risk Evaluation and Mitigation Strategy (REMS) is a strategy to manage known or potential serious risks associated with a drug product and is required by the Food and Drug Administration (FDA) to ensure that the benefits of the drug outweigh its risks. The goal of the XELJANZ REMS is to mitigate the risk of serious infections, malignancies, lymphoproliferative disorders, increased cholesterol, and low blood cell counts associated with Xeljanz by:.