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ZoBio - Drug Discovery Technology |

ZoBio offers Fragment-Based Drug Discovery research services on a fee-for-service basis to customers across the pharmaceutical & biotechnology industries.

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ZoBio - Drug Discovery Technology | | zobio.com Reviews
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ZoBio offers Fragment-Based Drug Discovery research services on a fee-for-service basis to customers across the pharmaceutical & biotechnology industries.
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1 integrated
2 drug discovery
3 platform
4 nmr based
5 structural
6 biology
7 solutions
8 rapid hit
9 identification
10 from fragment
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integrated,drug discovery,platform,nmr based,structural,biology,solutions,rapid hit,identification,from fragment,libraries,high resolution,structure,determination,by nmr,accelerate,your pipeline,with head,start projects,drug discovery platform,news,events
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ZoBio - Drug Discovery Technology | | zobio.com Reviews

https://zobio.com

ZoBio offers Fragment-Based Drug Discovery research services on a fee-for-service basis to customers across the pharmaceutical & biotechnology industries.

INTERNAL PAGES

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1

News | ZoBio - Drug Discovery Technology

http://www.zobio.com/category/news

Tools for fragment based drug discovery. VALIDATION & CHARACTERIZATION. HIT TO LEAD DEVELOPMENT. ZOBIO EXTENDS NMR STRUCTURAL BIOLOGY COLLABORATION WITH SANOFI. Comments Off on ZOBIO EXTENDS NMR STRUCTURAL BIOLOGY COLLABORATION WITH SANOFI. ZOBIO MOVES INTO BIOPARTNER 2 BUILDING. Comments Off on ZOBIO MOVES INTO BIOPARTNER 2 BUILDING. ZOBIO SECURES ADDITIONAL ACCESS TO HIGH FIELD NMR SPECTROMETERS THROUGH COLLABORATION WITH THE UNIVERSITY OF UTRECHT. ANNOUNCING HEAD START PROJECTS. HIGH THROUGHPUT PROTEI...

2

ZoBio Drug Discovery Platform | ZoBio - Drug Discovery Technology

http://www.zobio.com/drug-discovery-platform/hit-discovery/fragment-screening

Tools for fragment based drug discovery. VALIDATION & CHARACTERIZATION. HIT TO LEAD DEVELOPMENT. TARGET IMMOBILIZED NMR SCREENING. The orthogonal and quantitative nature has made SPR a powerful complement to our TINS fragment screening technology. Whereas TINS is capable of identifying fragments that bind to a target with very low affinity, SPR screening is well suited for molecules that potentially bind with higher affinity and is highly quantitative. ZoBio can implement a client’s assay or develo...

3

Head Start Projects | ZoBio - Drug Discovery Technology

http://www.zobio.com/head-start-projects/bromodomains

Tools for fragment based drug discovery. VALIDATION & CHARACTERIZATION. HIT TO LEAD DEVELOPMENT. In this project numerous validated, novel, ligand efficient starting points are available with full structural support from both X-ray crystallography and NMR. Moreover, these results demonstrate our ability to rapidly generate novel hits for essentially any BD and provide structural support using 2 independent methods for maximal robustness. ZOBIO EXTENDS NMR STRUCTURAL BIOLOGY COLLABORATION WITH SANOFI.

4

ZoBio Drug Discovery Platform | ZoBio - Drug Discovery Technology

http://www.zobio.com/drug-discovery-platform/hit-discovery/ligandibility-studies

Tools for fragment based drug discovery. VALIDATION & CHARACTERIZATION. HIT TO LEAD DEVELOPMENT. We and others (e.g. Hajduk,. Drug Disc. Today. Have noted a strong correlation between the hit rate (and hit diversity) in NMR fragment screening and the ligandability of a target. (Ligandability is often refered to as druggability, which includes more criteria other than ligand-target binding). ZoBio has developed its own correlation between TINS and ligandability as shown below. R (red) and β.

5

ANNOUNCING HEAD START PROJECTS | ZoBio - Drug Discovery Technology

http://www.zobio.com/announcing-head-start-projects

Tools for fragment based drug discovery. VALIDATION & CHARACTERIZATION. HIT TO LEAD DEVELOPMENT. ANNOUNCING HEAD START PROJECTS. ANNOUNCING HEAD START PROJECTS. 14 July 2015, Leiden, NL. This entry was posted in news. ZOBIO EXTENDS NMR STRUCTURAL BIOLOGY COLLABORATION WITH SANOFI. ZOBIO MOVES INTO BIOPARTNER 2 BUILDING. ZOBIO SECURES ADDITIONAL ACCESS TO HIGH FIELD NMR SPECTROMETERS THROUGH COLLABORATION WITH THE UNIVERSITY OF UTRECHT. ANNOUNCING HEAD START PROJECTS. Phone: 31 (0) 71 204 05 80.

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FBLD 2014

http://www.ysbl.york.ac.uk/fbld/2014

Fragment-based Lead Discovery Conference 2014. Basel, Switzerland, September 21. Welcome to FBLD 2014. Registration is now closed - the conference is FULL! Scientific program now available. FBLD 2014 will be held in Basel from 21-24 Sep 2014. This will be THE premiere fragment-based discovery conference for 2014 - organised by scientists for scientists. FBLD 2014 is being organised locally by Michael Hennig, Roche, and Wolfgang Jahnke, Novartis. And a flyer is available to download ( PDF. Back to the Top.

macbio.lic.leidenuniv.nl macbio.lic.leidenuniv.nl

Login | Macromolecular Biochemistry

http://macbio.lic.leidenuniv.nl/user

Enter your Macromolecular Biochemistry username. Enter the password that accompanies your username. Leiden Institute of Chemistry.

macbio.lic.leidenuniv.nl macbio.lic.leidenuniv.nl

Macromolecular Biochemistry

http://macbio.lic.leidenuniv.nl/teaching

Biochemie 1 (deel van CBI voor LST studenten). Fundamentals of NMR Spectroscopy. Leiden Institute of Chemistry.

macbio.lic.leidenuniv.nl macbio.lic.leidenuniv.nl

Available positions | Macromolecular Biochemistry

http://macbio.lic.leidenuniv.nl/vacancies

We regularly have positions available for PhD students, and, although less regularly, postdoctoral fellows. If you are interested in a PhD position in our group, please contact us. Leiden Institute of Chemistry.

drugdiscoverychemistry.com drugdiscoverychemistry.com

Fragment-Based Drug Discovery Conference

http://www.drugdiscoverychemistry.com/Fragment-Based-Drug-Discovery

From Hits to Leads and Lessons Learned. April 25-26, 2017 Sheraton San Diego Hotel and Marina. Scientific Advisor: Daniel A.Erlanson, Ph.D., Co-Founder,CarmotTherapeutics, Inc. Day 1 Day 2. Tuesday, April 25. FRAGMENTS TO LEADS AND CANDIDATES. Daniel A. Erlanson, Ph.D., Co-Founder, Carmot Therapeutics, Inc. Late-Breaking Presentation: Expanding the Ligandable Proteome: Ligand and Target Discovery by Fragment-Based Screening in Human Cells. Small molecule inhibitors of interleukin-1 receptor-associated ki...

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Glisten 2015

https://sites.google.com/site/glisten2015/home

Chair, WG leaders and LO. Call for Poster Abstracts. 1 - 2 April 2015. The GLISTEN Allschwil 2015 conference is organised by COST Action CM1207 and hosted by Actelion Pharmaceuticals Ltd. From 1-2 April, 2015. It is funded by COST. The GPCRDB satellite meeting will take place on 31 March and separated registration. Allschwil is located a few minutes from. A pharmaceutical hub at the center of Europe and can easily be reached by public transport from the city center (see Venue. GPCRs are the largest famil...

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Upcoming Cafes | Science meets Business

http://www.sciencemeetsbusiness.nl/category/upcoming

About the SmB cafe. SmB Club of 16. Life Sciences & Health. Water & Green Biotech. Chem & Biocatalysis. Instruments & Space. Category Archives: Upcoming Cafes. SmB 41 – Thursday 8 December 2016 – Themed Cafe Robotics. In December, Science meets Business will host its first themed cafe. Of the academic year. The cafe is dedicated entirely to robotics. We drafted an exciting programme for you! More speakers will be added. Dutch Nao Team – Patrick de Kok. Joost Broekens – TU Delft. RSVP is not yet open.

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Working with us — CRELUX

http://www.crelux.com/working-with-us

Only a few easy steps to your success. Only a few easy steps to your success. And take advantage of our world-class drug discovery and protein experience and start your project with us it is straightforward and easy! With us before disclosing any project details. You’ll receive comprehensive project proposal. That includes timelines, milestones, work steps and a payment plan within 10 days after having specified your request. During your project with us we keep you updated. A detailed written final report.

macbio.lic.leidenuniv.nl macbio.lic.leidenuniv.nl

Review published | Macromolecular Biochemistry

http://macbio.lic.leidenuniv.nl/news/review-published

Current Opinion in Structural Biology. Our review on the various isotope-labelling strategies in the study of macromolecular complexes by NMR. H Zhang and H. van Ingen. Isotope labeling strategies for solution NMR studies of macromolecular assemblies. Opinion in Structural Biology. 2016) 38, p. 75-82. Leiden Institute of Chemistry.

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