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ALSOD.IOP.KCL.AC.UK

ALSoD: Amyotrophic Lateral Sclerosis Online Genetics Database

Amyotrophic Lateral Sclerosis Online genetics Database

http://alsod.iop.kcl.ac.uk/

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ALSoD: Amyotrophic Lateral Sclerosis Online Genetics Database | alsod.iop.kcl.ac.uk Reviews
<META>
DESCRIPTION
Amyotrophic Lateral Sclerosis Online genetics Database
<META>
KEYWORDS
1 ALSoD
2 alsod
3 bioinformatics
4 genetics
5 ALS
6 MNDA
7 Motor Neurone Disease
8 ALSA
9 SOD1
10 ANG
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feedback,register,sitemap,cookies,media,print,cite us,gene overview,summary,genetic data report,gene maps,mutation maps,patient maps,gene discovery method,analysis,detailed analysis,interactions,side by side comparison,predict pathogenicity,data,genes
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ALSoD: Amyotrophic Lateral Sclerosis Online Genetics Database | alsod.iop.kcl.ac.uk Reviews

https://alsod.iop.kcl.ac.uk

Amyotrophic Lateral Sclerosis Online genetics Database

INTERNAL PAGES

alsod.iop.kcl.ac.uk alsod.iop.kcl.ac.uk
1

http://alsod.iop.kcl.ac.uk/maps/mutationmap.aspx

http://alsod.iop.kcl.ac.uk/Summary/patientmap.aspx

ALSoD vs ALSdb mutations. GWAS by Fogh 2013. Google Map showing location of patients with GENE. Institute of Psychiatry, Psychology and Neuroscience (IoPPN) DeCrespigny Park, Denmark Hill, London SE5 8AF.

2

http://alsod.iop.kcl.ac.uk/index.aspx

http://alsod.iop.kcl.ac.uk/jsmol/structures/structures.aspx

ALSoD vs ALSdb mutations. GWAS by Fogh 2013. Interacte with the generated image by right clicking on the image. For better viewing, right click on the TOP LEFT CORNER of the frame. Institute of Psychiatry, Psychology and Neuroscience (IoPPN) DeCrespigny Park, Denmark Hill, London SE5 8AF.

3

Frequently asked questions

http://alsod.iop.kcl.ac.uk/misc/FAQs.aspx

ALSoD vs ALSdb mutations. GWAS by Fogh 2013. The top 15 Frequently asked questions (FAQs). 1) What is ALSoD? 2) What is SOD1 ALS? 3) Why was ALSoD set up? 4) Who are the members/contributors? 5) How do I contact the ALSoD team? 6) How do I access the database? 7) Are my subject records private? 8) Can anyone submit data to the ALSoD database? 9) How do I submit data? 10) What kind of data may I add / does ALSoD store? 11) Are my subject records private? 13) What comprises a subject record? No At the mome...

4

ALSoD: Amyotrophic Lateral Sclerosis Online Genetics Database

http://alsod.iop.kcl.ac.uk/misc/penetrance.aspx

ALSoD vs ALSdb mutations. GWAS by Fogh 2013. CALCULATING PENETRANCE FOR ALS CASES. Please Note: the estimate is weighted by the proportion of UK families of size 1,2,.5. Percentage of fALS carrying variants e.g. 45. Percentage of sALS carrying variants e.g. 7. Al-Chalabi A, Lewis CM. Modelling the effects of penetrance and family size on rates of sporadic and familial disease. Hum Hered. 2011;71(4):281-8. doi: 10.1159/000330167.

5

Amyotrophic Lateral Sclerosis Online genetics Database

http://alsod.iop.kcl.ac.uk/maps/treeview.aspx

ALSoD vs ALSdb mutations. GWAS by Fogh 2013. GWAS by Fogh 2013. Institute of Psychiatry, Psychology and Neuroscience (IoPPN) DeCrespigny Park, Denmark Hill, London SE5 8AF.

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TOTAL PAGES IN THIS WEBSITE

19

LINKS TO THIS WEBSITE

alsresearchcenter.pitt.edu alsresearchcenter.pitt.edu

News & Events | Center for ALS Research | University of Pittsburgh

http://www.alsresearchcenter.pitt.edu/news

Live Like Lou Center for ALS Research at the University of Pittsburgh Brain Institute. Diaphragm Pacing Program and Study at UPMC. Melatonin Delays Disease Progression in an ALS Mouse Model. Zhang Y, Cook A, Kim K, et al. Melatonin inhibits the caspase-1/cytochrome c/caspase-3 cell death pathway, inhibits MT1 receptor loss and delays disease progression in a mouse model of amyotrophic lateral sclerosis. Neurobio Dis 2013; 55:26 35. Mutations account for about half of all cases of familial ALS.

alsclinic.pitt.edu alsclinic.pitt.edu

News & Events | Center for ALS Research | University of Pittsburgh

http://www.alsclinic.pitt.edu/news/index.php

Live Like Lou Center for ALS Research at the University of Pittsburgh Brain Institute. Diaphragm Pacing Program and Study at UPMC. Melatonin Delays Disease Progression in an ALS Mouse Model. Zhang Y, Cook A, Kim K, et al. Melatonin inhibits the caspase-1/cytochrome c/caspase-3 cell death pathway, inhibits MT1 receptor loss and delays disease progression in a mouse model of amyotrophic lateral sclerosis. Neurobio Dis 2013; 55:26 35. Mutations account for about half of all cases of familial ALS.

alsresearchcenter.pitt.edu alsresearchcenter.pitt.edu

News & Events | Center for ALS Research | University of Pittsburgh

http://www.alsresearchcenter.pitt.edu/news/index.php

Live Like Lou Center for ALS Research at the University of Pittsburgh Brain Institute. Diaphragm Pacing Program and Study at UPMC. Melatonin Delays Disease Progression in an ALS Mouse Model. Zhang Y, Cook A, Kim K, et al. Melatonin inhibits the caspase-1/cytochrome c/caspase-3 cell death pathway, inhibits MT1 receptor loss and delays disease progression in a mouse model of amyotrophic lateral sclerosis. Neurobio Dis 2013; 55:26 35. Mutations account for about half of all cases of familial ALS.

alsresearchcenter.org alsresearchcenter.org

News & Events | Center for ALS Research | University of Pittsburgh

http://www.alsresearchcenter.org/news

Live Like Lou Center for ALS Research at the University of Pittsburgh Brain Institute. Diaphragm Pacing Program and Study at UPMC. Melatonin Delays Disease Progression in an ALS Mouse Model. Zhang Y, Cook A, Kim K, et al. Melatonin inhibits the caspase-1/cytochrome c/caspase-3 cell death pathway, inhibits MT1 receptor loss and delays disease progression in a mouse model of amyotrophic lateral sclerosis. Neurobio Dis 2013; 55:26 35. Mutations account for about half of all cases of familial ALS.

alsresearchcenter.org alsresearchcenter.org

News & Events | Center for ALS Research | University of Pittsburgh

http://www.alsresearchcenter.org/news/index.php

Live Like Lou Center for ALS Research at the University of Pittsburgh Brain Institute. Diaphragm Pacing Program and Study at UPMC. Melatonin Delays Disease Progression in an ALS Mouse Model. Zhang Y, Cook A, Kim K, et al. Melatonin inhibits the caspase-1/cytochrome c/caspase-3 cell death pathway, inhibits MT1 receptor loss and delays disease progression in a mouse model of amyotrophic lateral sclerosis. Neurobio Dis 2013; 55:26 35. Mutations account for about half of all cases of familial ALS.

alsclinic.pitt.edu alsclinic.pitt.edu

News & Events | Center for ALS Research | University of Pittsburgh

http://www.alsclinic.pitt.edu/news

Live Like Lou Center for ALS Research at the University of Pittsburgh Brain Institute. Diaphragm Pacing Program and Study at UPMC. Melatonin Delays Disease Progression in an ALS Mouse Model. Zhang Y, Cook A, Kim K, et al. Melatonin inhibits the caspase-1/cytochrome c/caspase-3 cell death pathway, inhibits MT1 receptor loss and delays disease progression in a mouse model of amyotrophic lateral sclerosis. Neurobio Dis 2013; 55:26 35. Mutations account for about half of all cases of familial ALS.

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ALSoD: Amyotrophic Lateral Sclerosis Online Genetics Database

ALSoD vs ALSdb mutations. GWAS by Fogh 2013. Gene report of major ALS genes in ALSoD. Cu/Zn superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult). Amyotrophic lateral sclerosis 2 (juvenile) homolog (human). Alsin. Spastic paraplegia 11 (autosomal recessive). Fusion (involved in t(12;16) in malignant liposarcoma). Vesicle-associated membrane protein-associated protein B. TAR DNA binding protein. FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae).

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