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Richard Casey | Richard Casey
https://rmcsoftwareinc.wordpress.com/author/rmcsoftwareinc
Software Project Manager – HPC/Bioinformatics. This Blog is Moving! Posted by Richard Casey. Asymp; Leave a comment. For those of you who are subscribed to and following my blogsite, it is moving to a new website effective immediately. The new website is:. For continuity, all of my previous blogs have been migrated to the new site. And I will post all new blogs to the site as well. I hope you join me there! Genome Assembly without the RAM. Posted by Richard Casey. Asymp; 3 Comments. As an alternative to ...
rmcsoftwareinc.wordpress.com
Genome Assembly without the RAM | Richard Casey
https://rmcsoftwareinc.wordpress.com/2015/02/04/genome-assembly-without-the-ram
Software Project Manager – HPC/Bioinformatics. Genome Assembly without the RAM. Posted by Richard Casey. Asymp; 3 Comments. De novo assembly of Next Generation Sequencing (NGS). Assembling genomes with little memory. Is the construction of genomes without reference to existing known genomes. There is a wide variety of de novo assembly tools. From experience we know that some assemblers require several hundred GB (gigabytes) up to 1 TB (terabyte) of RAM,. Minia source code is available here. And the NCBI ...
gage.cbcb.umd.edu
GAGE
http://gage.cbcb.umd.edu//index.html
GAGE is an evaluation of the very latest large-scale genome assembly algorithms. We have organized this "bake-off" as an attempt to produce a realistic assessment of genome assembly software in a rapidly changing field of next-generation sequencing. The main results of GAGE have now been published in the journal. GAGE: A critical evaluation of genome assemblies and assembly algorithms. Why do we need GAGE? How much sequencing coverage do I need for my genome project? Here are some differences:. We will c...
biomcmc.blogspot.com
bioMCMC: Testing for common ancestry
http://biomcmc.blogspot.com/2012/05/testing-for-common-ancestry.html
Rambling notes on Bayesian Procedures in Biology. Tuesday, May 15, 2012. Testing for common ancestry. Our commentary on Douglas Theobald's test from Universal Common Ancestry (UCA) just went online. The original idea was to make a user-friendly review of his analysis described in " A formal test of the theory of universal common ancestry. Using a curated set of genes highly conserved among all three domains, his test indicated that UCA is a much better explanation than IO, and that each gene is better re...
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