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Blog - Latest News. October 22, 2014. Cynomolgus Monkey as Host for the Prediction of Drug Transporter Interactions. Written by Marton Jani, SOLVO Biotechnology. The following monkey drug transporter proteins have been cloned and characterized. As of mid 2014: OAT1, OAT3, OATP1B1, OATP1B3, OATP2B1, MRP1, MRP2, P-gp. 2-3 fold) between human and monkey when applying verapamil and quinidine as inhibitors, digoxin and cyclosporine A as probes. (Takeuchi et al 2006, Suzuyama et al 2007). Primary hepatocytes h...

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