dsysmap.irbbarcelona.org

dSysMap

In this way it is possible to identify those mutations that are found at the interface between two proteins and, therefore, might have an effect on the way they interact." /. Mapping of Human disease-related mutations at the systemic level. The current version of dSysMap. Is this you first time with dSysMap? Take a 5 minutes Tutorial! Tutorial : Learn how to use dSysMap. Select a disease from the following list. Query with a list of proteins. Enter a list of proteins (Uniprot AC or gene name).

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dSysMap | dsysmap.irbbarcelona.org Reviews

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In this way it is possible to identify those mutations that are found at the interface between two proteins and, therefore, might have an effect on the way they interact. /. Mapping of Human disease-related mutations at the systemic level. The current version of dSysMap. Is this you first time with dSysMap? Take a 5 minutes Tutorial! Tutorial : Learn how to use dSysMap. Select a disease from the following list. Query with a list of proteins. Enter a list of proteins (Uniprot AC or gene name).

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1 dsysmap

2 disease map

3 mutation

4 3d

5 interactome

6 edgetic mutation

7 edgetic

8 disease

9 edge related mutation

10 systemic map

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browse,download,stats,tutorial,please wait,dsysmap,browse diseases,example loeys dietz syndrome,no results found,example,click here to,continue the tutorial,submit your mutations

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dSysMap | dsysmap.irbbarcelona.org Reviews

https://dsysmap.irbbarcelona.org

In this way it is possible to identify those mutations that are found at the interface between two proteins and, therefore, might have an effect on the way they interact." /. Mapping of Human disease-related mutations at the systemic level. The current version of dSysMap. Is this you first time with dSysMap? Take a 5 minutes Tutorial! Tutorial : Learn how to use dSysMap. Select a disease from the following list. Query with a list of proteins. Enter a list of proteins (Uniprot AC or gene name).

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dsysmap.irbbarcelona.org

1

dSysMap - Download

http://dsysmap.irbbarcelona.org/download.php

Download the data for a set of proteins. Enter a list of proteins (Uniprot AC or gene name). For example. C3 CFB CFH. Please introduce a correct list of Uniprot ACs or gene names, separated by spaces. Also make sure that the Uniprot ACs that you have entered refer to the correct version of Uniprot. Download the data for a disease. Select a disease from the list. Download the entire dataset. If you want to download the entire dataset including all the disease mutations. Last modified: 15 October 2014.

2

dSysMap - Statistics

http://dsysmap.irbbarcelona.org/statistics.php

Statistics on dSysMap (ver. 2016 06). Version of source databases. Mutations in predicted disordered regions. Representation of MeSH categories. Diseases (clusters of phenotypes). Phenotypes with muts. on structures. Diseases with muts. on structures. Proteins in the human proteome. Proteins affected by disease mutations. Mutated proteins with structural data. Mutated proteins with complete structures. Mutated proteins with complete models. Mutated proteins with partial struct/models. Mutations in a diso...

3

dSysMap

http://dsysmap.irbbarcelona.org/index.php

In this way it is possible to identify those mutations that are found at the interface between two proteins and, therefore, might have an effect on the way they interact." /. Mapping of Human disease-related mutations at the systemic level. The current version of dSysMap. Is this you first time with dSysMap? Take a 5 minutes Tutorial! Tutorial : Learn how to use dSysMap. Select a disease from the following list. Query with a list of proteins. Enter a list of proteins (Uniprot AC or gene name).

4

dSysMap Test - Network for disease 'Brachydactyly'

http://dsysmap.irbbarcelona.org/tour.html

Network for disease Brachydactyly [15 proteins and 19 interactions]. Protein with complete structure. Protein with complete model. Protein with partial structs/models. Protein without structural data. Protein with buried mutations. Protein with surface mutations (that cannot be mapped to an interface). Interaction with experimental structure. Interaction with model (from global template). Interaction with model (from domain-domain template). Interaction without structural data. A disorder characterized b...

5

dSysMap - About

http://dsysmap.irbbarcelona.org/about.php

DsysMap is provided by the Structural Bioinformatics and Network Biology Group. At the Institute for Research in Biomedicine. Mosca R, Tenorio-Laranga J, Olivella R, Alcalde V, Céol A, Soler-López M and Aloy P. DSysMap: exploring the edgetic role of disease mutations. 2015, Nature Methods, 12:167-168, doi:10.1038/nmeth.328. Http:/ dsysmap.irbbarcelona.org. For any question or suggestion please send an email to dsysmap. Last modified: 27 February 2015.

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El Blog de la RSC: febrero 2015

http://responsabilidadsocialcorp.blogspot.com/2015_02_01_archive.html

Si Adam Smith afirmaba que maximizar el "YO" maximizaba el "NOSOTROS", la RSC afirma que maximizar el "NOSOTROS" maximiza el "YO". La Responsabilidad Social Corporativa (RSC) refleja una nueva dimensión de la empresa preocupada en su sostenibilidad y no tanto en el corto plazo. Una triple visión -económica, social y medioambiental- que prima el desarrollo sostenible. Sábado, 28 de febrero de 2015. 62 Jornada Corresponsables, Madrid. Ángel Fraile, Isabel Garro, Laura Prieto y Encarni Rodríguez. Denunciar ...

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Stem Cell: febrero 2015

http://stemcellizpisua.blogspot.com/2015_02_01_archive.html

Blog de aula. Biología 2º Bachillerato - IES Izpisua Belmonte (Hellín - Spain). Sábado, 28 de febrero de 2015. Un mapa que relaciona 23.000 mutaciones genéticas con enfermedades. El Instituto de Investigación Biomédica (IRB) de Barcelona ha desarrollado una herramienta computacional que permite por primera vez relacionar las 23.000 mutaciones genéticas documentadas hasta ahora en el mundo, que afectan la función de 2.000 proteínas, con las enfermedades que provocan. La plataforma se denomina. El 80 % de ...

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dSysMap: mapping mutations on the human structural interactome | Structural Bioinformatics and Network Biology Group

http://sbnb.irbbarcelona.org/node/130

Skip to main content. DSysMap: mapping mutations on the human structural interactome. DSysMap (which stands for Disease-mutations Systemic Mapping ) is a computational tool to interpret the effect of genetic mutations on the development of complex diseases by mapping them to the human structural interactome. dSysMap allows to display mutations in the systemic context of the human interactome and to identify their potential "edgetic" effects. Http:/ dsysmap.irbbarcelona.org.

sbnb.irbbarcelona.org

Resources | Structural Bioinformatics and Network Biology Group

http://sbnb.irbbarcelona.org/resources

Skip to main content. Our webservers and other resources. The database of three-dimensional interacting domains. 3did) is a collection of protein interactions for which high-resolution three-dimensional structures. Are known. 3did exploits the a availability of structural data to provide molecular details on interactions between two globular domains as well as novel domain peptide interactions. The complex nature of biological systems requires intricate networks of protein-protein interactions that coord...

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dsysmap.irbbarcelona.org

dSysMap

In this way it is possible to identify those mutations that are found at the interface between two proteins and, therefore, might have an effect on the way they interact." /. Mapping of Human disease-related mutations at the systemic level. The current version of dSysMap. Is this you first time with dSysMap? Take a 5 minutes Tutorial! Tutorial : Learn how to use dSysMap. Select a disease from the following list. Query with a list of proteins. Enter a list of proteins (Uniprot AC or gene name).

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