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leask-lab.mcgill.ca

Leask Lab

Prof Richard L Leask. Associate Professor, William Dawson Scholar. Department of Chemical Engineering. 3610 University St. Montreal QC H3A 2B2. The laboratory is also involved in the metabolomics of common xeonobiotics. We are investigating the biodegradation of plasticizers and pharmaceuticals to better understand the potential for toxic biotransfomation. This information is being used to re-engineer plasticizing compounds to avoid toxic metabolites, thus creating green plasticizers. 3th CSChE Ontario-Q...

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Leask Lab | leask-lab.mcgill.ca Reviews
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Prof Richard L Leask. Associate Professor, William Dawson Scholar. Department of Chemical Engineering. 3610 University St. Montreal QC H3A 2B2. The laboratory is also involved in the metabolomics of common xeonobiotics. We are investigating the biodegradation of plasticizers and pharmaceuticals to better understand the potential for toxic biotransfomation. This information is being used to re-engineer plasticizing compounds to avoid toxic metabolites, thus creating green plasticizers. 3th CSChE Ontario-Q...
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Leask Lab | leask-lab.mcgill.ca Reviews

https://leask-lab.mcgill.ca

Prof Richard L Leask. Associate Professor, William Dawson Scholar. Department of Chemical Engineering. 3610 University St. Montreal QC H3A 2B2. The laboratory is also involved in the metabolomics of common xeonobiotics. We are investigating the biodegradation of plasticizers and pharmaceuticals to better understand the potential for toxic biotransfomation. This information is being used to re-engineer plasticizing compounds to avoid toxic metabolites, thus creating green plasticizers. 3th CSChE Ontario-Q...

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leask-lab.mcgill.ca leask-lab.mcgill.ca
1

Leask Lab

http://leask-lab.mcgill.ca/publications.html

Last Updated Sept 2013. Cooper S, Jonak P, Chouinard-Pelletier G, Coulombe S, Jones E, Leask RL. Permeabilization of adhered cells using an inert gas jet. 2013 Sep 4;(79). doi: 10.3791/50612. Nobari S, Mongrain R, Leask R, Cartier R. The effect of aortic wall and aortic leaflet stiffening on coronary hemodynamic: a fluid-structure interaction study. Med Biol Eng Comput. 2013 Apr 3. [Epub ahead of print]. Dick M, Jonak P,. Erythropel HC, Dodd P,. Chouinard-Pelletier G, Leduc M, Guay D. Mongrain R, Gaillar...

2

Leask Lab

http://leask-lab.mcgill.ca/teaching.html

Last Updated June 2013. CHEE 314 - Fluid Mechanics: Core Chemical Engineering undergraduate course. CHEE 651 - Advanced Biochemical Engineering: Core Chemical Engineering Graduate Course (with E. Jones). CHEE 694 - Oral Presenation Skills: Chemical Engineering Grauduate Course. CHEE/MECH 563 - Biofluids and Cardiovascular Mechanics (with R. Mongrain). CHEE 314 - Fluid Mechanics (Core Chemical Engineering undergraduate course). CHEE 694 - Oral Presenation Skills: Chemical Engineering Grauduate Course.

3

Leask Lab

http://leask-lab.mcgill.ca/Biomechanics.html

Biomechanics of the Ascending Aorta. 1 Nobari S, Mongrain R, Leask R, Cartier R. The effect of aortic wall and aortic leaflet stiffening on coronary hemodynamic: a fluid-structure interaction study. Med Biol Eng Comput. 2 Nobari S, Mongrain R, Gaillard E, Leask R, Cartier R. Therapeutic vascular compliance change may cause significant variation in coronary perfusion: a numerical study. Comput Math Methods Med. 9 Slack G, Cohen J, Lenkei-Kerwin SS, David T, Leask R, Butany J. Images in Cardiology....

4

Leask Lab

http://leask-lab.mcgill.ca/biodegradation.html

1 Erythropel HC, Dodd P,. Leask RL, Maric M, Cooper DG. Designing green plasticizers: influence of alkyl chain length on biodegradation and plasticization properties of succinate based plasticizers. Chemosphere. 2013 Apr;91(3):358-65. doi: 10.1016/j.chemosphere.2012.11.061. Epub 2013 Jan 20. 2Piche CD, Sauvageau D, Vanlian M, Erythropel HC, Robaire B, Leask RL. Effects of di-(2-ethylhexyl) phthalate and four of its metabolites on steroidogenesis in MA-10 cells. 4 Yargeau V, Huot JC.

5

Leask Lab

http://leask-lab.mcgill.ca/devices.html

Cell Permeabilization: We have shown that a jet of non-thermal plasma and inert gas can temporarily permeabilize adherent cells. 1 Chouinard-Pelletier G, Leduc M, Guay D. Coulombe S, Leask RL, Jones EA. (2012) Use of inert gas jets to measure the forces required for mechanical gene transfection. Biomed Eng Online 2012;11:67. 2 Leduc M, Guay D. Coulombe S, Leask RL. (2010) Effects of non-thermal plasmas on DNA and mammalian cells, Plasma Processes and Polymers 2010;7(11) 899-909. Leduc M. 4 Leduc M, Guay D.

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Leask Lab

Prof Richard L Leask. Associate Professor, William Dawson Scholar. Department of Chemical Engineering. 3610 University St. Montreal QC H3A 2B2. The laboratory is also involved in the metabolomics of common xeonobiotics. We are investigating the biodegradation of plasticizers and pharmaceuticals to better understand the potential for toxic biotransfomation. This information is being used to re-engineer plasticizing compounds to avoid toxic metabolites, thus creating green plasticizers. 3th CSChE Ontario-Q...

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