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For Health Care Professionals. NEED FOR NEW TREATMENTS. IRX-2, THE IMMUNE SYSTEM, AND CANCER. IRX-2, THE IMMUNE SYSTEM, AND CANCER. THE IMMUNE SYSTEM FIGHTS CANCER. IRX-2 MAY STRENGTHEN THE IMMUNE SYSTEM. HOW IRX-2 IS GIVEN. TO THE INSPIRE PATIENT SITE. IRX-2, THE IMMUNE SYSTEM, AND CANCER.

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For Health Care Professionals. NEED FOR NEW TREATMENTS. IRX-2, THE IMMUNE SYSTEM, AND CANCER. IRX-2, THE IMMUNE SYSTEM, AND CANCER. THE IMMUNE SYSTEM FIGHTS CANCER. IRX-2 MAY STRENGTHEN THE IMMUNE SYSTEM. HOW IRX-2 IS GIVEN. TO THE INSPIRE PATIENT SITE. IRX-2, THE IMMUNE SYSTEM, AND CANCER.
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Home - IRX Inspire HNSCC | patient.inspirehnc.com Reviews

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For Health Care Professionals. NEED FOR NEW TREATMENTS. IRX-2, THE IMMUNE SYSTEM, AND CANCER. IRX-2, THE IMMUNE SYSTEM, AND CANCER. THE IMMUNE SYSTEM FIGHTS CANCER. IRX-2 MAY STRENGTHEN THE IMMUNE SYSTEM. HOW IRX-2 IS GIVEN. TO THE INSPIRE PATIENT SITE. IRX-2, THE IMMUNE SYSTEM, AND CANCER.

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1

What is Oral Cancer? - IRX Inspire HNSCC

http://patient.inspirehnc.com/oral-cancer

For Health Care Professionals. NEED FOR NEW TREATMENTS. IRX-2, THE IMMUNE SYSTEM, AND CANCER. IRX-2, THE IMMUNE SYSTEM, AND CANCER. THE IMMUNE SYSTEM FIGHTS CANCER. IRX-2 MAY STRENGTHEN THE IMMUNE SYSTEM. HOW IRX-2 IS GIVEN. What is Oral Cancer? Need for New Treatments. Oral cancer is part of a group of cancers that affect the head and neck. Cancer is called oral cancer if it starts in:. The inside lining of the lips and cheeks. The front two-thirds of the tongue. The floor of the mouth below the tongue.

2

IRX-2, THE IMMUNE SYSTEM, AND CANCER - IRX Inspire HNSCC

http://patient.inspirehnc.com/immune-system

For Health Care Professionals. NEED FOR NEW TREATMENTS. IRX-2, THE IMMUNE SYSTEM, AND CANCER. IRX-2, THE IMMUNE SYSTEM, AND CANCER. THE IMMUNE SYSTEM FIGHTS CANCER. IRX-2 MAY STRENGTHEN THE IMMUNE SYSTEM. HOW IRX-2 IS GIVEN. IRX-2, THE IMMUNE SYSTEM, AND CANCER. The Immune System Fights Cancer. IRX-2 May Strengthen the Immune System. How IRX-2 is Given. Messengers, which send messages between different types of cells. Fighters, which kill other cells. Regulators, which turn other cells on or off.

3

Need for New Treatments - IRX Inspire HNSCC

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For Health Care Professionals. NEED FOR NEW TREATMENTS. IRX-2, THE IMMUNE SYSTEM, AND CANCER. IRX-2, THE IMMUNE SYSTEM, AND CANCER. THE IMMUNE SYSTEM FIGHTS CANCER. IRX-2 MAY STRENGTHEN THE IMMUNE SYSTEM. HOW IRX-2 IS GIVEN. What is Oral Cancer? Need for New Treatments. NEW TREATMENTS FOR ORAL CANCER. Standard treatments help many people with oral cancer feel better and live longer. However, in many cases, they are not able to kill all the cancer or to prevent it from coming back.

4

Treatments - IRX Inspire HNSCC

http://patient.inspirehnc.com/treatments

For Health Care Professionals. NEED FOR NEW TREATMENTS. IRX-2, THE IMMUNE SYSTEM, AND CANCER. IRX-2, THE IMMUNE SYSTEM, AND CANCER. THE IMMUNE SYSTEM FIGHTS CANCER. IRX-2 MAY STRENGTHEN THE IMMUNE SYSTEM. HOW IRX-2 IS GIVEN. What is Oral Cancer? Need for New Treatments. Before starting treatment, your doctor will probably perform many tests. These tests will help your doctor understand your cancer. Your doctor will perform a careful examination of your mouth, throat, and the surrounding areas. Immunother...

5

Find Support - IRX Inspire HNSCC

http://patient.inspirehnc.com/support

For Health Care Professionals. NEED FOR NEW TREATMENTS. IRX-2, THE IMMUNE SYSTEM, AND CANCER. IRX-2, THE IMMUNE SYSTEM, AND CANCER. THE IMMUNE SYSTEM FIGHTS CANCER. IRX-2 MAY STRENGTHEN THE IMMUNE SYSTEM. HOW IRX-2 IS GIVEN. INFORMATION AND SUPPORT TO FIGHT ORAL CANCER. Here are some sources of information and support for people with oral cancer:. AMERICAN CANCER SOCIETY (US). Web: http:/ www.cancer.org/cancer/oralcavityandoropharyngealcancer/index. ORAL CANCER FOUNDATION (US). Web: www.spohnc.org.

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FAQs - IRX Inspire HNSCC

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IRX-2 & IRX-2 REGIMENS. IMMUNE SYSTEM IN HNSCC. HUMORAL VS CELLULAR IMMUNITY. WHY IS THE IRX-2 NEOADJUVANT REGIMEN ADMINISTERED LOCALLY? The IRX-2 Neoadjuvant Regimen is administered locally to promote uptake of endogenous tumor peptides by dendritic cells (DCs) and subsequent T-cell activation during the first treatment cycle. WHY IS THE IRX-2 NEOADJUVANT REGIMEN INITIATED PRIOR TO CURATIVE SURGERY? Accommodations will be provided or reimbursed for patients whose location requires them to be away from h...

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Inspire Videos - IRX Inspire HNSCC

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IRX-2 & IRX-2 REGIMENS. IMMUNE SYSTEM IN HNSCC. HUMORAL VS CELLULAR IMMUNITY.

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MOA - IRX Inspire HNSCC

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IRX-2 & IRX-2 REGIMENS. IMMUNE SYSTEM IN HNSCC. HUMORAL VS CELLULAR IMMUNITY. THE NEED FOR MULTIPLE MECHANISMS OF ACTION IN CANCER IMMUNOTHERAPY. Given the numerous cellular defects present in cancer, IRX believes that any single receptor cannot restore all cellular immune responses. Therefore:. Must be enlisted for an effective cellular immune response. There may be a benefit to a biologic with multiple active components versus a single cytokine. IRX-2 MECHANISMS OF ACTION. IRX-2 MECHANISMS OF ACTION.

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Humoral vs Cellular Immunity - IRX Inspire HNSCC

http://hcp.inspirehnc.com/humoral-v-cellular

IRX-2 & IRX-2 REGIMENS. IMMUNE SYSTEM IN HNSCC. HUMORAL VS CELLULAR IMMUNITY. HUMORAL VS CELLULAR IMMUNITY. The immune system can be broadly divided into a cellular and a humoral response. The cellular immune response relies on T cells, whereas the humoral immune response involves antibodies. Most cancer vaccines are directed at achieving a cellular immune response.

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Immunity in HNSCC - IRX Inspire HNSCC

http://hcp.inspirehnc.com/immunity-in-hnscc

IRX-2 & IRX-2 REGIMENS. IMMUNE SYSTEM IN HNSCC. HUMORAL VS CELLULAR IMMUNITY. HUMORAL VS CELLULAR IMMUNITY. IN HEAD and NECK SQUAMOUS CELL CARCINOMA. Subjects with head and neck cancer are consistently immunocompromised. At the time of presentation. Hadden JW et al.

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Administration - IRX Inspire HNSCC

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IRX-2 & IRX-2 REGIMENS. IMMUNE SYSTEM IN HNSCC. HUMORAL VS CELLULAR IMMUNITY. ADMINISTRATION OF IRX-2 AS PART OF THE NEOADJUVANT REGIMEN. In head and neck squamous cell carcinoma, the IRX-2 biologic is injected into the mastoid region and drains into the lymphatic vessels, where physiologic quantities of IRX-2 restore the lymph node microenvironment and enable dendritic cells (DCs) to activate T cells against endogenous tumor peptides that have drained to the lymph node.

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Cellular Immunity - IRX Inspire HNSCC

http://hcp.inspirehnc.com/cellular-immunity

IRX-2 & IRX-2 REGIMENS. IMMUNE SYSTEM IN HNSCC. HUMORAL VS CELLULAR IMMUNITY. HUMORAL VS CELLULAR IMMUNITY. In a healthy immune system, the cellular immune response works to clear foreign pathogens every day. Immature dendritic cells (DCs) ingest disease antigens, then migrate to lymph nodes where they mature. The mature DCs activate naïve T cells and create cytotoxic T cells. The cytotoxic T cells proliferate, enter the circulation, search out, and kill the antigenic target.

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Regimen Overview - IRX Inspire HNSCC

http://hcp.inspirehnc.com/regimen-overview

Unlink(/home/solstic9/public html/hcp/wp-content/uploads/grid-gallery/cache/locales): No such file or directory in /home/solstic9/public html/hcp/wp-content/plugins/grid-gallery-ready/vendor/Rsc/Cache/Filesystem.php. Cannot modify header information - headers already sent by (output started at /home/solstic9/public html/hcp/wp-content/plugins/grid-gallery-ready/vendor/Rsc/Cache/Filesystem.php:73) in /home/solstic9/public html/hcp/wp-content/plugins/sg-cachepress/class-sg-cachepress.php. Following neoadju...

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Immune System Overview - IRX Inspire HNSCC

http://hcp.inspirehnc.com/immune-system-overview

IRX-2 & IRX-2 REGIMENS. IMMUNE SYSTEM IN HNSCC. HUMORAL VS CELLULAR IMMUNITY. HUMORAL VS CELLULAR IMMUNITY. IN HEAD and NECK SQUAMOUS CELL CARCINOMA. The immune system is a mechanism by which an organism differentiates between self (its own tissues) and non-self (everything else) and protects against non-self. Cancer cells originate as self, but as they convert from normal cells into cancer cells, they develop new and different proteins or peptides on their cell surface.

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Home - IRX Inspire HNSCC

For Health Care Professionals. NEED FOR NEW TREATMENTS. IRX-2, THE IMMUNE SYSTEM, AND CANCER. IRX-2, THE IMMUNE SYSTEM, AND CANCER. THE IMMUNE SYSTEM FIGHTS CANCER. IRX-2 MAY STRENGTHEN THE IMMUNE SYSTEM. HOW IRX-2 IS GIVEN. TO THE INSPIRE PATIENT SITE. IRX-2, THE IMMUNE SYSTEM, AND CANCER.

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View, download your medical documents and securely send documents to other provider. Send, receive, and document messages to stay in touch with your provider. Get answers to your medical questions privately from your clinic. View details of your past as well as future appointments, request to schedule or cancel your appointments. View the laboratory or diagnostic tests ordered by your provider for you. Also view the results once they are available. Don’t have an account yet? Having trouble logging in?

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PATIENT.IT

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I want to . Learn About My Doctor. Patient's Bill of Rights. Please change your password since your PIN number is soon expired. You can switch user on the top to view your family member's medical record and messages with doctors.

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Meditab Services

View, download your medical documents and securely send documents to other provider. Send, receive, and document messages to stay in touch with your provider. Get answers to your medical questions privately from your clinic. View details of your past as well as future appointments, request to schedule or cancel your appointments. View the laboratory or diagnostic tests ordered by your provider for you. Also view the results once they are available. Don’t have an account yet? Having trouble logging in?