PortaCellTec provides a broad spectrum of hepatic/renal uptake transporter assays (e.g. OATs, OCTs, OATPs) to investigate the inhibitor and substrate characteristics of drugs. As recommended by FDA and EMA we perform in vitro transporter studies with validated drug transporters stably transfected in HEK293 cells.
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PortaCellTec | portacelltec.de Reviews
https://portacelltec.de
PortaCellTec provides a broad spectrum of hepatic/renal uptake transporter assays (e.g. OATs, OCTs, OATPs) to investigate the inhibitor and substrate characteristics of drugs. As recommended by FDA and EMA we perform in vitro transporter studies with validated drug transporters stably transfected in HEK293 cells.
portacelltec.de
PortaCellTec
http://www.portacelltec.de/addService.php
Analyzes of gene expression (e.g. CYP-Induction, Transporters) in different cells (e.g. hepatocytes or tumor cells) by qPCR. Stable transfection of HEK293-cells with gene of interest. Solubility test of the test item. Test for stickiness of the test item. Weender Landstraße 94 -108. Tel : 49 551 309 66440. March 06-09, 2017. Bad Herrenalb, Germany. May 15-17, 2017. Köln, Germany. June 26- 29, 2017. Symposium on Transporters in Drug Discovery. May 15-16, 2017. Münster Transporttage 2017.
PortaCellTec
http://www.portacelltec.de/events.php
Meet our experts at the following events:. 2016 February 29 - March 3, Berlin, Germany. AAPS/ITC-Workshop on Drug Transporters. 2016 April 18-20, Baltimore, USA. 18th Barrier- and Transporter-Meeting. 2016 May 02-04, Bad Herrenalb, Germany. 2016 September, Göttingen, Germany. AAPS/ITC Workshop on Drug Transporter. 2015 April 20-22, Baltimore, USA. 2015 August 9-13, 2015, Lugano, Switzerland. 17th Barrier- and Transporter-Meeting. 2015 May 11-13, Bad Herrenalb, Germany. Göttinger Transporttage,. Gött...
PortaCellTec
http://www.portacelltec.de/experform.php
Using genetically modified human kidney cell lines we provide interaction studies of drugs with specific transporter proteins. Because of new FDA guidelines, the characterization of clinically relevant drug transporters is gaining an increasing importance during drug approval process. To characterize drug transporter interactions we provide the following studies:. Uptake transporter assay for all SLC-Transporters. Vesicle-based transporter assay for BCRP and BSEP. Rhodamine 123 efflux assay is used to ex...
PortaCellTec
http://www.portacelltec.de/board.php
Prof Dr. Gerhard Burckhardt. Expert on organic anion transporters (OATs). Professor and head of the department of Vegetative Physiology and Pathophysiology, Georg-August-Universität Göttingen (since 1991). Habilitation for physiology (1988). Coordinator for graduate college cancer pharmacogenetics (gcpg 1034; since 2005). Current focus: regulation and substrate binding of OAT1 and NaDC3. Link: http:/ www.veg-physiol.med.uni-goettingen.de/. Prof Dr. Hermann Koepsell. Habilitation for Biochemistry (1987).
PortaCellTec
http://www.portacelltec.de/literatur.php
Organic Anion Transporters (OATs). Rizwan AN, Burckhardt G. 2007. Organic anion transporters of the SLC22 family: Biopharmaceutical, physiological, and pathological roles. Pharmaceutical Research 24:450-470. Burckhardt BC, Burckhardt G. 2003. Transport of organic anions across the basolateral membrane of proximal tubule cells. Reviews of Physiology, Biochemistry and Pharmacology, Vol 146 146:95-158. Organic Cation Transporters (OCTs). Koepsell H, Lips K, Volk C. 2007. Polyspecific organic cation ...Koeps...
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Domain Names
PortaCellTec
PortaCellTec – the pathfinder for your drug. PortaCellTec (PCT) provides a broad spectrum of uptake and efflux transporter assays (e.g. OATs, OCTs, OATPs, MATEs, MDR1, BCRP, BSEP, MRPs) to investigate the inhibitory potential and substrate characteristics of your drug. As recommended by FDA and EMA, we perform. Transporter studies with validated drug transporters stably-transfected in HEK-293 cells. Quantification of non-labeled substances by LC/MS. Ko143, elacridar,. Weender Landstraße 94 -108.
PortaCellTec
PortaCellTec – the pathfinder for your drug. PortaCellTec (PCT) provides a broad spectrum of uptake and efflux transporter assays (e.g. OATs, OCTs, OATPs, MATEs, MDR1, BCRP, BSEP, MRPs) to investigate the inhibitory potential and substrate characteristics of your drug. As recommended by FDA and EMA, we perform. Transporter studies with validated drug transporters stably-transfected in HEK-293 cells. Quantification of non-labeled substances by LC/MS. Ko143, elacridar,. Weender Landstraße 94 -108.
PortaCellTec
PortaCellTec – the pathfinder for your drug. PortaCellTec (PCT) provides a broad spectrum of uptake and efflux transporter assays (e.g. OATs, OCTs, OATPs, MATEs, MDR1, BCRP, BSEP, MRPs) to investigate the inhibitory potential and substrate characteristics of your drug. As recommended by FDA and EMA, we perform. Transporter studies with validated drug transporters stably-transfected in HEK-293 cells. Quantification of non-labeled substances by LC/MS. Ko143, elacridar,. Weender Landstraße 94 -108.
PortaCellTec
PortaCellTec – the pathfinder for your drug. PortaCellTec (PCT) provides a broad spectrum of uptake and efflux transporter assays (e.g. OATs, OCTs, OATPs, MATEs, MDR1, BCRP, BSEP, MRPs) to investigate the inhibitory potential and substrate characteristics of your drug. As recommended by FDA and EMA, we perform. Transporter studies with validated drug transporters stably-transfected in HEK-293 cells. Quantification of non-labeled substances by LC/MS. Ko143, elacridar,. Weender Landstraße 94 -108.
PortaCellTec
PortaCellTec – the pathfinder for your drug. PortaCellTec (PCT) provides a broad spectrum of uptake and efflux transporter assays (e.g. OATs, OCTs, OATPs, MATEs, MDR1, BCRP, BSEP, MRPs) to investigate the inhibitory potential and substrate characteristics of your drug. As recommended by FDA and EMA, we perform. Transporter studies with validated drug transporters stably-transfected in HEK-293 cells. Quantification of non-labeled substances by LC/MS. Ko143, elacridar,. Weender Landstraße 94 -108.
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