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PORTACELLTEC.ORG

PortaCellTec

PortaCellTec provides a broad spectrum of hepatic/renal uptake transporter assays (e.g. OATs, OCTs, OATPs) to investigate the inhibitor and substrate characteristics of drugs. As recommended by FDA and EMA we perform in vitro transporter studies with validated drug transporters stably transfected in HEK293 cells.

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CONTACTS AT PORTACELLTEC.ORG

PortaCellTec

Yohannes Hagos

Humbo●●●●●ee 23

Goe●●●gen , 37073

DE

49.5●●●●5894
49.5●●●●5883
ha●●●@portacelltec.de

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PortaCellTec

Yohannes Hagos

Humbo●●●●●ee 23

Goe●●●gen , 37073

DE

49.5●●●●5894
49.5●●●●5883
ha●●●@portacelltec.de

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PortaCellTec | portacelltec.org Reviews
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PortaCellTec provides a broad spectrum of hepatic/renal uptake transporter assays (e.g. OATs, OCTs, OATPs) to investigate the inhibitor and substrate characteristics of drugs. As recommended by FDA and EMA we perform in vitro transporter studies with validated drug transporters stably transfected in HEK293 cells.
<META>
KEYWORDS
1 Organic anion transporter
2 Organic cation transporter
3 Drug transporter
4 Transporter assays
5 Transport proteins
6 Hepatic uptake transporter
7 Renal uptake transporter
8 Drug interaction
9 Inhibition
10 IC50
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portacelltec,service,drug transporter assays,additional service,partnered service,drug transporter,drug uptake transporter,drug efflux transporter,references,about us,team,events,important milestones,scientific advisory board,advice and assistance,imprint
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PortaCellTec | portacelltec.org Reviews

https://portacelltec.org

PortaCellTec provides a broad spectrum of hepatic/renal uptake transporter assays (e.g. OATs, OCTs, OATPs) to investigate the inhibitor and substrate characteristics of drugs. As recommended by FDA and EMA we perform in vitro transporter studies with validated drug transporters stably transfected in HEK293 cells.

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portacelltec.org portacelltec.org
1

PortaCellTec

http://www.portacelltec.org/events.php

Meet our experts at the following events:. 2017 March 06-09, Heidelberg, Germany. 2017 May 15-17, Bad Herrenalb, Germany. 2017 June 26- 29, Köln, Germany. Symposium on Transporters in Drug Discovery. 2017 May 15-16, London, UK. 2016 February 29 - March 3, Berlin, Germany. AAPS/ITC-Workshop on Drug Transporters. 2016 April 18-20, Baltimore, USA. 18th Barrier- and Transporter-Meeting. 2016 May 02-04, Bad Herrenalb, Germany. 2016 September, Göttingen, Germany. AAPS/ITC Workshop on Drug Transporter. Weender ...

2

PortaCellTec

http://www.portacelltec.org/milestones.php

In May 2012, PD Dr. Yohannes Hagos (CEO of PortaCellTec biosciences) was awarded by the business region Goettingen with the “Gute Gründe(r)” price. Wolfgang Meyer (Mayor of Goettingen), Klaus Hoffmann (CEO of GWG) and Detlev Barth (CEO of WRG) handed him the award for the implementation of an innovative and viable business idea. Over 3 years PortaCellTec successfully provides drug transporter assays. BMBF program “. Development of efflux transporter assays – founded 3 years 2012 - 2015.

3

PortaCellTec

http://www.portacelltec.org/publications.php

Beta-2 adrenergic-agonists are substrates and inhibitors of human organic cation transporter 1. Salomon, Johanna; Hagos, Yohannes; Petzke, Sören; Kühne, Annett; Gausterer, Julia; Hosoya, Ken-ichi; Ehrhardt, Carsten. Journal: Molecular Pharmaceutics in press 2015. Interaction of human organic anion transporter polypeptides 1B1 and 1B3 with antineoplastic compounds. Marada VV, Flörl S, Kühne A, Burckhardt G, Hagos Y. Eur J Med Chem. 2015 Mar 6. Tel : 49 551 395894. German Pharm-Tox Summit 2016.

4

PortaCellTec

http://www.portacelltec.org/experform.php

Using genetically modified human kidney cell lines we provide interaction studies of drugs with specific transporter proteins. Because of new FDA guidelines, the characterization of clinically relevant drug transporters is gaining an increasing importance during drug approval process. To characterize drug transporter interactions we provide the following studies:. Uptake transporter assay for all SLC-Transporters. Vesicle-based transporter assay for BCRP and BSEP. Rhodamine 123 efflux assay is used to ex...

5

PortaCellTec

http://www.portacelltec.org/board.php

Prof Dr. Gerhard Burckhardt. Expert on organic anion transporters (OATs). Professor and head of the department of Vegetative Physiology and Pathophysiology, Georg-August-Universität Göttingen (since 1991). Habilitation for physiology (1988). Coordinator for graduate college cancer pharmacogenetics (gcpg 1034; since 2005). Current focus: regulation and substrate binding of OAT1 and NaDC3. Link: http:/ www.veg-physiol.med.uni-goettingen.de/. Prof Dr. Hermann Koepsell. Habilitation for Biochemistry (1987).

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PortaCellTec

PortaCellTec – the pathfinder for your drug. PortaCellTec (PCT) provides a broad spectrum of uptake and efflux transporter assays (e.g. OATs, OCTs, OATPs, MATEs, MDR1, BCRP, BSEP, MRPs) to investigate the inhibitory potential and substrate characteristics of your drug. As recommended by FDA and EMA, we perform. Transporter studies with validated drug transporters stably-transfected in HEK-293 cells. Quantification of non-labeled substances by LC/MS. Ko143, elacridar,. Weender Landstraße 94 -108.

portacelltec.de portacelltec.de

PortaCellTec

PortaCellTec – the pathfinder for your drug. PortaCellTec (PCT) provides a broad spectrum of uptake and efflux transporter assays (e.g. OATs, OCTs, OATPs, MATEs, MDR1, BCRP, BSEP, MRPs) to investigate the inhibitory potential and substrate characteristics of your drug. As recommended by FDA and EMA, we perform. Transporter studies with validated drug transporters stably-transfected in HEK-293 cells. Quantification of non-labeled substances by LC/MS. Ko143, elacridar,. Weender Landstraße 94 -108.

portacelltec.info portacelltec.info

PortaCellTec

PortaCellTec – the pathfinder for your drug. PortaCellTec (PCT) provides a broad spectrum of uptake and efflux transporter assays (e.g. OATs, OCTs, OATPs, MATEs, MDR1, BCRP, BSEP, MRPs) to investigate the inhibitory potential and substrate characteristics of your drug. As recommended by FDA and EMA, we perform. Transporter studies with validated drug transporters stably-transfected in HEK-293 cells. Quantification of non-labeled substances by LC/MS. Ko143, elacridar,. Weender Landstraße 94 -108.

portacelltec.net portacelltec.net

PortaCellTec

PortaCellTec – the pathfinder for your drug. PortaCellTec (PCT) provides a broad spectrum of uptake and efflux transporter assays (e.g. OATs, OCTs, OATPs, MATEs, MDR1, BCRP, BSEP, MRPs) to investigate the inhibitory potential and substrate characteristics of your drug. As recommended by FDA and EMA, we perform. Transporter studies with validated drug transporters stably-transfected in HEK-293 cells. Quantification of non-labeled substances by LC/MS. Ko143, elacridar,. Weender Landstraße 94 -108.

portacelltec.org portacelltec.org

PortaCellTec

PortaCellTec – the pathfinder for your drug. PortaCellTec (PCT) provides a broad spectrum of uptake and efflux transporter assays (e.g. OATs, OCTs, OATPs, MATEs, MDR1, BCRP, BSEP, MRPs) to investigate the inhibitory potential and substrate characteristics of your drug. As recommended by FDA and EMA, we perform. Transporter studies with validated drug transporters stably-transfected in HEK-293 cells. Quantification of non-labeled substances by LC/MS. Ko143, elacridar,. Weender Landstraße 94 -108.

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