xceleron.com

Xceleron

The Power of AMS. Xceleron’s analytical power accelerates your development program, saves you time and money, and moves your product forward with confidence. Xceleron is a world leader in the use of Accelerator Mass Spectrometry (AMS) analytical technology in pharmaceutical, food technology, crop protection and biobased product applications. IVPK Studies in Phase II/III. Accelerating the development programs of clients worldwide. View Case Studies ». Read Client Quotes ». AMS is a unique analytical platf...

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CONTACTS AT XCELERON.COM

Xceleron Ltd

Hague Jeremy

York Biocentr●●●●●●●●●●●●●ay Heslington

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in●●@nts2000.com

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Xceleron Ltd

Hague Jeremy

York Biocentr●●●●●●●●●●●●●ay Heslington

Y●k , YO10 5NY

GB

44.1●●●●1561

in●●@nts2000.com

View this contact

Xceleron Ltd

Hague Jeremy

York Biocentr●●●●●●●●●●●●●ay Heslington

Y●k , YO10 5NY

GB

44.1●●●●1561

in●●@nts2000.com

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Xceleron | xceleron.com Reviews

<META> DESCRIPTION

The Power of AMS. Xceleron’s analytical power accelerates your development program, saves you time and money, and moves your product forward with confidence. Xceleron is a world leader in the use of Accelerator Mass Spectrometry (AMS) analytical technology in pharmaceutical, food technology, crop protection and biobased product applications. IVPK Studies in Phase II/III. Accelerating the development programs of clients worldwide. View Case Studies ». Read Client Quotes ». AMS is a unique analytical platf...

<META> KEYWORDS

1 about us

2 our team

3 services

4 pharmaceutical services

5 clients

6 overview

7 proof of concept

8 asset sale

9 asset purchase

10 drug approval

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about us,our team,services,pharmaceutical services,clients,overview,proof of concept,asset sale,asset purchase,drug approval,client quotes,news,resources,publications,presentations,webinars,what we do,learn more,technology and expertise,r&d efficiency

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Xceleron | xceleron.com Reviews

https://xceleron.com

The Power of AMS. Xceleron’s analytical power accelerates your development program, saves you time and money, and moves your product forward with confidence. Xceleron is a world leader in the use of Accelerator Mass Spectrometry (AMS) analytical technology in pharmaceutical, food technology, crop protection and biobased product applications. IVPK Studies in Phase II/III. Accelerating the development programs of clients worldwide. View Case Studies ». Read Client Quotes ». AMS is a unique analytical platf...

INTERNAL PAGES

xceleron.com

1

Xceleron | Asset sale

http://www.xceleron.com/asset-sale

The Power of AMS. Asset sale strategies tend to be pursued predominantly smaller drug development companies seeking to generate income from their early development pipelines. For this reason, many of our asset sales case studies are similar to those for proof-of-concept. The same principles of simple investigational design and robust analytical insight are used in this context to show value to a potential buyer. Helped to design iterative microdose clinical approach. Conducted all AMS analyses. Chromatog...

2

Xceleron | IVPK Studies in Phase II/III

http://www.xceleron.com/services/phase-ii-iii-clinical-trials/ivpk-studies-phase-ii-iii

The Power of AMS. IVPK Studies in Phase II/III. April 18, 2011. Saving Cost and Time With IV Tracers and AMS. International regulators particularly from the EU, Japan and Australia are increasingly requesting absolute bioavailability. Data in Phase II and Phase III. Obtaining this data using the traditional cross-over clinical design can take up to a year and $1.5M to allow for IV toxicity evaluations, IV formulation development and GMP manufacture. Read more ». What our clients are saying about us.

3

Xceleron | Publications

http://www.xceleron.com/category/resources/publications

The Power of AMS. AstraZeneca – Incorporation of an IV [14C]-microtracer dose into a first in human study to determine the absolute oral bioavailability of AZD5122. Retrieve the paper from here. Concomitant Oral And Intravenous Pharmacokinetics Of Dabrafenib, A BRAF Inhibitor, In Patients With BRAF V600 Mutation-positive Solid Tumors. Published: J Clin Pharmacol. 2013 Sep;53(9):955-61. Denton CL, Minthorn E, Carson SW, Young GC, Richards-Peterson LE, Botbyl J, Han C, Morrison RA, Blackman SC, Ouellet D.

4

Xceleron | Proof-of-concept

http://www.xceleron.com/proof-of-concept-case-studies

The Power of AMS. We have conducted proof-of-concept studies for a range of small and large pharmaceutical companies. The following case studies demonstrate how simple study design combined with the AMS platform may be applied to your development program. Our customers have saved years and significant expense by using a microtracer and AMS in either a pharmacological-dose or microdose setting. Anti-infective AR-709 to treat MRSA in the upper respiratory tract. Full project management of compound. De-risk...

5

Xceleron | Xceleron Experience Gets Drugs to Market

http://www.xceleron.com/clients

The Power of AMS. Xceleron Experience Gets Drugs to Market. To date, Xceleron has worked on over 200 molecules for over 100 clients, from small biotech to large pharma. The first drug to use AMS data in regulatory filing was marketed in 1999. Drugs Registered Using AMS Data. Roche/Genentech hedgehog pathway inhibitor registered for the treatment of basal cell carcinoma by the FDA in January, 2012. Xceleron did AMS analysis on both absolute bioavailability and mass balance for the regulatory submission.

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drugtestingconference.com

Speed and Safety in Drug Discovery

http://www.drugtestingconference.com/links.html

Press Coverage and Proceedings. The proceedings of our conference were published by FRAME (Fund for the Replacement of Animals in Medical Experiments) as a supplement to a special issue of Alternatives to Laboratory Animals. They are available for free here. Or please contact us for free hard copies. On our Royal Society conference by Dr Nirmala Bhogal, Scientific Director of FRAME was published in the February issue of. Alternatives to Laboratory Animals. Were published in the February issue of.

pk-pd.blogspot.com

PK/PD: Phase 0 Microdosing/Microtracing in Phase 1 Studies

http://pk-pd.blogspot.com/2009/06/phase-0-microdosingmicrotracing-in.html

A blog with random discussions on pharmacokinetics, pharmacodynamics and drug development. Tuesday, June 9, 2009. Phase 0 Microdosing/Microtracing in Phase 1 Studies. Stephen Dueker, PhD, President/CEO of Vitalea Science. Recently commented on my previous post on Microdosing Studies. What needs to be understood is that AMS is much more than Phase 0. N, etc.can all be ascertained in a microdosing study. This indeed is what the specificity of a tracer and the sensitivity of AMS uncover. It is everyone&#821...

pelletron.com

Links to Pelletrons

http://www.pelletron.com/link2.html

Links to Labs with Pelletrons. Departamento de Física Nuclear. 8UD at Universidade de São Paulo in São Paulo, Brazil. Department of Nuclear Physics. 14UD at Australia National University in Canberra, Australia (14UD photo). Holifield Radioactive Ion Beam Facility. 25URC at Oak Ridge National Laboratory in Oak Ridge, Tennessee. Comisión Nacional de Energía Atómica. 20UD in Buenos Aires, Argentina. UTTAC, Tandem Accelerator Center. 12UD at University of Tsukuba in Tsukuba, Japan. 14UD in Mumbai, India.

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Xceleron

The Power of AMS. Xceleron’s analytical power accelerates your development program, saves you time and money, and moves your product forward with confidence. Xceleron is a world leader in the use of Accelerator Mass Spectrometry (AMS) analytical technology in pharmaceutical, food technology, crop protection and biobased product applications. IVPK Studies in Phase II/III. Accelerating the development programs of clients worldwide. View Case Studies ». Read Client Quotes ». AMS is a unique analytical platf...

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Xceleron’s analytical power accelerates your development program, saves you time and money, and moves your product forward with confidence. Xceleron is a world leader in the use of Accelerator Mass Spectrometry (AMS) analytical technology in pharmaceutical, food technology, crop protection and biobased product applications. Xceleron can help you to design and implement preclinical and clinical fit-for-purpose investigations. Our clients regularly use us to meet commercial objectives associated with:.

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